Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.74 |
| ▸ | NR3C2 | P08235 | 12/20 | 0.74 |
| ▸ | PGR | P06401 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436547 | 0.86 | NR3C1 (0.55) | NR3C1NR3C2PGR | |
| SCHEMBL5520847 | 0.85 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL6908248 | 0.81 | NR3C1 (0.73) | NR3C1NR3C2PGR | |
| SCHEMBL3654089 | 0.80 | NR3C1 (0.57) | NR3C1NR3C2PGR | |
| SCHEMBL6912427 | 0.78 | NR3C1 (0.77) | NR3C1NR3C2PGR | |
| SCHEMBL4039578 | 0.78 | NR3C1 (0.71) | NR3C1NR3C2PGR | |
| SCHEMBL5524358 | 0.78 | NR3C1 (0.87) | NR3C1NR3C2PGR | |
| SCHEMBL3684708 | 0.77 | NR3C1 (0.51) | NR3C1NR3C2PGR | |
| SCHEMBL5521730 | 0.75 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL5522517 | 0.75 | NR3C1 (1.00) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490317-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003082787-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-10-09 | — | — | WO | disclosed |