Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.51 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 4/20 | 0.46 |
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332462 | 0.91 | ZDHHC7 (0.46) | SIRT1SIRT6NOD1 | |
| SCHEMBL369214 | 0.90 | SIRT1 (0.50) | SIRT1SIRT6GNAI3GNAO1GNAI1 | |
| SCHEMBL15715750 | 0.89 | DPP7 (0.42) | DPP7NOD1 | |
| SCHEMBL27546189 | 0.88 | SIRT1 (0.51) | SIRT1SIRT6GNAI3GNAO1GNAI1 | |
| SCHEMBL5916980 | 0.85 | SIRT1 (0.46) | SIRT1SIRT6GNAI3GNAO1GNAI1 | |
| SCHEMBL5916984 | 0.85 | SIRT1 (0.46) | SIRT1SIRT6GNAI3GNAO1GNAI1 | |
| SCHEMBL27451758 | 0.84 | SIRT1 (0.51) | SIRT1SIRT6GNAI3GNAO1GNAI1 | |
| Acetic Acid SCHEMBL27357036 | 0.84 | SIRT1 (0.54) | SIRT1SIRT6GNAI3GNAO1GNAI1 | |
| SCHEMBL17831010 | 0.84 | CYP1A2 (0.53) | SIRT1SIRT6GNAI3GNAO1GNAI1 | |
| SCHEMBL367558 | 0.83 | NOD1 (0.56) | SIRT1SIRT6GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937100-B2 | Cosmetic composition containing calcium citrate and N-acylated aminoalcohol derivative | COGNIS IP MANAGEMENT GMBH (DE) | 2015-01-20 | — | — | US | disclosed |
| US-20140086863-A1 | Cosmetic Composition | COGNIS IP MANAGEMENT GMBH (DE) | 2014-03-27 | — | — | US | disclosed |
| US-8592484-B2 | Cosmetic composition containing calcium citrate and N-acylated aminoalcohol derivative to prevent dry skin and signs of cutaneous ageing | COGNIS IP MANAGEMENT GMBH (DE) | 2013-11-26 | — | — | US | disclosed |
| EP-2410977-A1 | COSMETIC COMPOSITION CONTAINING CALCIUM CITRATE AND N-ACYLATED AMINOALCOHOL DERIVATIVE TO PREVENT DRY SKIN AND SIGNS OF CUTANEOUS AGEING | Cognis IP Management GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| US-20120016032-A1 | Cosmetic Composition Containing Calcium Citrate And N-Acylated Aminoalcohol Derivative To Prevent Dry Skin And Signs Of Cutaneous Ageing | COGNIS IP MANAGEMENT GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
| WO-2010108619-A1 | COSMETIC COMPOSITION CONTAINING CALCIUM CITRATE AND N-ACYLATED AMINOALCOHOL DERIVATIVE TO PREVENT DRY SKIN AND SIGNS OF CUTANEOUS AGEING | COGNIS IP MANAGEMENT GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |
| EP-2233128-A1 | Cosmetic composition | Cognis IP Management GmbH (DE) | 2010-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140086863-A1 | Cosmetic Composition | ASAH2, ASAH1, GLA | SIRT1 257/4885SIRT6 548/4885GNAI3 3229/4885 |
| US-20120016032-A1 | Cosmetic Composition Containing Calcium Citrate And N-Acylated Aminoalcohol Derivative To Prevent Dry Skin And Signs Of Cutaneous Ageing | ASAH2, ASAH1, GLA | SIRT1 284/4885SIRT6 533/4885GNAI3 3197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.