Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | MARS1 | P56192 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16519490 | 0.82 | KMT2A (0.61) | KMT2ATSHRGAATP53ALDH1A1 | |
| SCHEMBL3687891 | 0.67 | KMT2A (0.62) | KMT2ATSHRGAAALDH1A1ALOX15 | |
| SCHEMBL11217089 | 0.67 | ALDH1A1 (0.47) | KMT2ATSHRGAAALDH1A1MAPT | |
| SCHEMBL2578103 | 0.65 | LMNA (0.47) | GAAALDH1A1ALOX15HSD17B10LMNA | |
| SCHEMBL111808 | 0.64 | ALDH1A1 (0.67) | KMT2AGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL1155953 | 0.64 | LMNA (0.42) | TSHRTP53ALDH1A1ALOX15KDM4E | |
| SCHEMBL13715783 | 0.63 | ALDH1A1 (0.50) | KMT2AGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL29452123 | 0.63 | ALDH1A1 (0.55) | GAAALDH1A1ALOX15HTTLMNA | |
| SCHEMBL18754429 | 0.63 | LMNA (0.68) | GAAALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL26982634 | 0.63 | LMNA (0.49) | KMT2AGAATP53ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2187748-B1 | FUNGICIDAL COMPOUNDS AND MIXTURES | DU PONT (US) | 2017-07-05 | — | — | EP | disclosed |
| CN-104663674-A | Fungicidal Mixtures | DU PONT | 2015-06-03 | — | — | CN | disclosed |
| CN-101969781-B | Fungicidal compounds and mixtures | DU PONT | 2015-01-28 | — | — | CN | disclosed |
| US-8449898-B2 | Fungicidal mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-28 | — | — | US | disclosed |
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CORTEVA AGRISCIENCE LLC | 2010-09-23 | — | — | US | disclosed |
| EP-2187748-A2 | FUNGICIDAL COMPOUNDS AND MIXTURES | E. I. du Pont de Nemours and Company (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009055514-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CYP1B1, CYP1A1, NOX1 | KMT2A 2074/4885TSHR 2769/4885GAA 726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.