Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.47 |
| ▸ | FNTB | P49356 | 15/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.34 |
| ▸ | NRAS | P01111 | 1/20 | 0.34 |
| ▸ | HRAS | P01112 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154511 | 1.00 | FNTA (0.47) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL8147142 | 0.99 | FNTA (0.46) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3501299 | 0.92 | FNTA (0.56) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3685883 | 0.92 | FNTA (0.56) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3684995 | 0.92 | FNTA (0.56) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL9082057 | 0.91 | FNTA (0.55) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL8155159 | 0.89 | FNTA (0.39) | FNTAFNTBCYP19A1 | |
| Hydrochloric Acid SCHEMBL8141557 | 0.89 | FNTA (0.39) | FNTAFNTBCYP19A1 | |
| SCHEMBL8006493 | 0.86 | FNTA (0.53) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3500218 | 0.86 | FNTA (0.53) | FNTAFNTBPGGT1BNRASHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000070083-A1 | ASSAY FOR MYELOSUPPRESSION BY FARNESYL TRANSFERASE INHIBITORS | MERCK & CO., INC. (US) | 2000-11-23 | — | — | WO | disclosed |