SCHEMBL3685553

SCHEMBL3685553

Cc1cc(C)c(C(=O)P(=O)(C(=O)c2ccccc2)C(=O)c2ccccc2)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.41
MEN1 O00255 3/20 0.41
LMNA P02545 3/20 0.41
HPGD P15428 2/20 0.41
CES2 O00748 2/20 0.40
CES1 P23141 2/20 0.40
LCK P06239 1/20 0.40
NPSR1 Q6W5P4 2/20 0.39
RAB9A P51151 2/20 0.39
MAPT P10636 2/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
NPC1 O15118 1/20 0.39
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28338390 0.88 SMN1; SMN2 (0.44) KMT2ASMN1; SMN2MEN1LMNAHPGD
SCHEMBL21352322 0.85 KMT2A (0.40) KMT2ASMN1; SMN2MEN1LMNAHPGD
SCHEMBL3195966 0.85 TAS1R3 (0.43) KMT2ASMN1; SMN2MEN1LMNAHPGD
SCHEMBL21352369 0.84 KMT2A (0.40) KMT2ASMN1; SMN2MEN1LMNAHPGD
SCHEMBL30460025 0.84 KMT2A (0.40) KMT2ASMN1; SMN2MEN1LMNAHPGD
SCHEMBL10387059 0.81 HPGD (0.41) KMT2ASMN1; SMN2MEN1HPGDRAB9A
Benzophenone SCHEMBL17435222 0.81 HPGD (0.43) KMT2ASMN1; SMN2MEN1LMNAHPGD
Benzophenone SCHEMBL5496913 0.81 KMT2A (0.43) KMT2ASMN1; SMN2MEN1LMNAHPGD
Benzophenone SCHEMBL3324674 0.80 ALDH1A1 (0.58) KMT2ASMN1; SMN2MEN1LMNAHPGD
SCHEMBL7565852 0.79 ALDH1A1 (0.60) KMT2ASMN1; SMN2MEN1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997027223-A1 PROCESS FOR PREPARING OPTICAL ARTICLES SOLA INTERNATIONAL HOLDINGS LTD. (AU) 1997-07-31 WO claimed
JP-2248470-A None JP disclosed
US-7666955-B2 Methods for producing branched-polyether resin composition and acid pendant branched-polyether resin composition DAINIPPON INK AND CHEMICALS, INC. (JP) 2010-02-23 US disclosed
US-20090131622-A1 Method For Producing Branched-Polyether Resin Composition And Method For Producing Acid Pendant Branched-Polyether Resin Composition DAINIPPON INK AND CHEMICALS, INC. (JP) 2009-05-21 US disclosed
EP-1261886-B1 METHODS AND COMPOSITIONS FOR THE MANUFACTURE OF OPHTHALMIC LENSES ESSILOR INT (FR) 2009-04-15 EP disclosed
EP-1297035-B1 COMPOSITIONS AND METHODS FOR THE MANUFACTURE OF OPHTHALMIC LENSES JOHNSON & JOHNSON VISION CARE (US) 2005-02-16 EP disclosed
US-6630083-B1 Methods and compositions for the manufacture of ophthalmic lenses JOHNSON & JOHNSON VISION CARE, INC. 2003-10-07 US disclosed
EP-1297035-A1 COMPOSITIONS AND METHODS FOR THE MANUFACTURE OF OPHTHALMIC LENSES Johnson & Johnson Vision Care, Inc. (US) 2003-04-02 EP disclosed
EP-1261886-A1 METHODS AND COMPOSITIONS FOR THE MANUFACTURE OF OPHTHALMIC LENSES ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2002-12-04 EP disclosed
EP-0759448-B1 Ionizing radiation-curable resin composition for optical article, optical article, and surface light source DAINIPPON PRINTING CO LTD (JP) 2002-01-30 EP disclosed
WO-2001085812-A1 COMPOSITIONS AND METHODS FOR THE MANUFACTURE OF OPHTHALMIC LENSES JOHNSON & JOHNSON VISION CARE, INC. (US) 2001-11-15 WO disclosed
WO-2001046717-A1 METHODS AND COMPOSITIONS FOR THE MANUFACTURE OF OPHTHALMIC LENSES JOHNSON & JOHNSON VISION CARE, INC. (US) 2001-06-28 WO disclosed
US-5714218-A AN EPOXYACRYLATE HAVING CYCLIC STRUCTURE CONTAINING ATLEAST TWO ACRYLATE GROUPS AND MONOFUNCTIONAL ACRYLATE HAVING CYCLIC STRUCTURE; HIGH SURFACE HARDNESS, REFRACTIVE INDEX AND FREE FROM DEFORMATION DAINIPPON PRINTING CO., LTD. (JP) 1998-02-03 US disclosed
WO-1997027223-A1 PROCESS FOR PREPARING OPTICAL ARTICLES SOLA INTERNATIONAL HOLDINGS LTD. (AU) 1997-07-31 WO disclosed
EP-0759448-A1 Ionizing radiation-curable resin composition for optical article, optical article, and surface light source Dainippon Printing Co., Ltd. (JP) 1997-02-26 EP disclosed
JP-H02248470-A RESIN COMPOSITION FOR COATING OPTICAL FIBER SUMITOMO CHEM CO LTD 1990-10-04 JP disclosed