Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396824 | 0.94 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Ethylene Glycol SCHEMBL505625 | 0.88 | TSHR (0.45) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Methacrylic Acid SCHEMBL28241961 | 0.88 | TSHR (0.45) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Trimethylammonium SCHEMBL7640981 | 0.86 | TSHR (0.44) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Methacrylic Acid SCHEMBL29221162 | 0.85 | TET2 (0.36) | TSHRTHRBALDH1A1TET2 | |
| SCHEMBL19433445 | 0.82 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| Methacrylic Acid SCHEMBL18037940 | 0.82 | TSHR (0.41) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Ethylene Glycol SCHEMBL16669550 | 0.82 | TSHR (0.38) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Methacrylic Acid SCHEMBL7207924 | 0.82 | TSHR (0.44) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL29221164 | 0.81 | ALDH1A1 (0.47) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616073-A | Hydrophobic dental composites based on a polyfluorinated dental resin | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1986-10-07 | — | — | US | claimed |
| JP-3124707-A | — | — | None | — | — | JP | disclosed |
| US-20240209168-A1 | MONOMER COMPOSITION, MOLDED BODY, BONDED MAGNET, DUST CORE | RESONAC CORPORATION (JP) | 2024-06-27 | — | — | US | disclosed |
| US-20240074945-A1 | CURABLE COMPOSITION FOR DENTAL RESTORATION | KURARAY NORITAKE DENTAL INC. (JP) | 2024-03-07 | — | — | US | disclosed |
| CN-117500656-A | System and method for stereolithography three-dimensional printing | 霍洛公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2024014437-A1 | CURABLE COMPOSITION, CURED PRODUCT, AND DENTAL MATERIAL | 三井化学株式会社 | 2024-01-18 | — | — | WO | disclosed |
| CN-117067579-A | Sensor for three-dimensional printing system and method | 霍洛公司 | 2023-11-17 | — | — | CN | disclosed |
| EP-4268797-A1 | CURABLE COMPOSITION FOR DENTAL RESTORATION | Kuraray Noritake Dental Inc. (JP) | 2023-11-01 | — | — | EP | disclosed |
| US-11784544-B2 | Method of manufacturing laminated steel plate | THREEBOND CO., LTD. (JP) | 2023-10-10 | — | — | US | disclosed |
| CN-112533963-B | (meth) acrylate, monomer composition for dental material, molded article, composition for dental material, and method for producing (meth) acrylate | 三井化学株式会社 | 2023-07-25 | — | — | CN | disclosed |
| US-20040254258-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| US-6759495-B2 | HIGH FLUIDITY AND EXCELLENT PROCESSABILITY SUCH AS VACUUM FORMING | CHI MEI CORPORATION (TW) | 2004-07-06 | — | — | US | disclosed |
| US-20040102579-A1 | Thermoplastic styrenic resin composition | SU WEN-YI (TW) | 2004-05-27 | — | — | US | disclosed |
| US-20040054079-A1 | Heat resistance; impact strength; melt processability; uniform wall thickness | CHI MEI CORPORATION (TW) | 2004-03-18 | — | — | US | disclosed |
| CN-1468899-A | Serial thermoplastic polystyrene resin compositions | 奇美实业股份有限公司 | 2004-01-21 | — | — | CN | disclosed |
| US-5923397-A | INTERPENETRATING NETWORK OF CROSSLINKED ACRYLIC POLYMERS; RIGID GAS PERMEABLE CORE SECTION AND SOFT EDGE SECTION ATTACHED ANNULARLY ABOUT THE CORE SECTION; EASIER TO CLEAN, PROVID GREATER VISION ACUITY AND GREATER COMFORT | BAUSCH & LOMB INCORPORATED (US) | 1999-07-13 | — | — | US | disclosed |
| JP-H03124707-A | PRODUCTION OF MOLDING COMPOSITION AND MOLDING | SANYO CHEM IND LTD | 1991-05-28 | — | — | JP | disclosed |
| EP-0423998-A2 | Composite and moulded articles therefrom | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |
| US-4616073-A | Hydrophobic dental composites based on a polyfluorinated dental resin | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1986-10-07 | — | — | US | disclosed |
| US-4517278-A | 1,2-POLYBUTADIENE CROSSLINKED WITH AN ACRYLIC ESTER | NIPPON PAINT CO., LTD. (JP) | 1985-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240074945-A1 | CURABLE COMPOSITION FOR DENTAL RESTORATION | SMCHD1, WDR26, KAT6A | TSHR 3667/4885THRB 2516/4885ALDH1A1 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.