Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CETP | P11597 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2812180 | 0.98 | CYP2D6 (0.55) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL28876360 | 0.98 | CYP2D6 (0.55) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL28319046 | 0.98 | CYP2D6 (0.55) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL2806965 | 0.98 | CYP2D6 (0.55) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL2811312 | 0.98 | CYP2D6 (0.55) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL5907187 | 0.93 | ALDH1A1 (0.46) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL3873681 | 0.86 | LMNA (0.48) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL9626184 | 0.85 | SPHK1 (0.60) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL25421950 | 0.85 | CYP2D6 (0.52) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL30018032 | 0.84 | SPHK1 (0.48) | CYP2D6SPHK1LMNATP53GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206933-B1 | Compositions comprising caprylyl glycol and iodopropynyl butylcarbamate | JOHNSON & JOHNSON CONSUMER FR (FR) | 2006-05-17 | — | — | EP | claimed |
| US-7854940-B2 | A mixture of caprylyl glycol with a preservative comprising chloroxylenol and 2- phenoxyethanol; effective activity against Pseudomonas aeruginosa, Entamoeba gingivere, Candida albicans and Aspergillus niger; shelf life of personal care products, cosmetics | ARCH CHEMICALS, INC. (US) | 2010-12-21 | — | — | US | disclosed |
| EP-1788869-A2 | BROAD SPECTRUM PRESERVATION BLENDS | Arch Chemicals, Inc. (US) | 2007-05-30 | — | — | EP | disclosed |
| EP-0809492-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-1206933-B1 | Compositions comprising caprylyl glycol and iodopropynyl butylcarbamate | JOHNSON & JOHNSON CONSUMER FR (FR) | 2006-05-17 | — | — | EP | disclosed |
| WO-2006033970-A2 | BROAD SPECTRUM PRESERVATION BLENDS | ARCH CHEMICALS, INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| US-20060057175-A1 | A mixture of caprylyl glycol with a preservative comprising chloroxylenol and 2- phenoxyethanol; effective activity against Pseudomonas aeruginosa, Entamoeba gingivere, Candida albicans and Aspergillus niger; shelf life of personal care products, cosmetics | ARCH CHEMICALS, INC. | 2006-03-16 | — | — | US | disclosed |
| EP-1238651-B1 | Agents for potentiating preservatives in sunscreen formulations | JOHNSON & JOHNSON CONSUMER FR (FR) | 2005-10-05 | — | — | EP | disclosed |
| EP-1238651-A1 | Agents for potentiating preservatives in sunscreen formulations | Johnson & Johnson Consumer France SAS (FR) | 2002-09-11 | — | — | EP | disclosed |
| EP-1206933-A1 | Compositions comprising caprylyl glycol and preservatives | Johnson & Johnson Consumer France SAS (FR) | 2002-05-22 | — | — | EP | disclosed |
| EP-0809492-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025157-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-22 | — | — | WO | disclosed |