SCHEMBL3686104

SCHEMBL3686104

CCON=C(C(=O)O)c1ccccc1COc1ccc(C=C(Cl)Cl)cc1Br

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 5/20 0.41
MRGPRX4 Q96LA9 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
RAB9A P51151 2/20 0.40
HTT P42858 3/20 0.38
ALDH1A1 P00352 2/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 4/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 2/20 0.37
POLB P06746 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
FOLH1 Q04609 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
NPC1 O15118 1/20 0.36
HPGD P15428 1/20 0.36
TLR9 Q9NR96 1/20 0.36
PTPN7 P35236 1/20 0.36
CACNA1B Q00975 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3686965 0.91 HIF1A (0.42) HIF1AMRGPRX4SMN1; SMN2RAB9AHTT
SCHEMBL3688079 0.90 MRGPRX4 (0.48) HIF1AMRGPRX4SMN1; SMN2RAB9AHTT
SCHEMBL3694297 0.90 HIF1A (0.42) HIF1AMRGPRX4SMN1; SMN2HTTTP53
SCHEMBL3688432 0.90 MAPT (0.46) HIF1AMRGPRX4SMN1; SMN2RAB9AHTT
SCHEMBL3683991 0.89 HIF1A (0.54) HIF1AMRGPRX4SMN1; SMN2RAB9AALDH1A1
SCHEMBL16440090 0.88 PTGDR2 (0.42) HIF1AMRGPRX4SMN1; SMN2RAB9AHTT
SCHEMBL3751654 0.84 HIF1A (0.52) HIF1ASMN1; SMN2RAB9AALDH1A1MEN1
SCHEMBL3755609 0.84 NR1H4 (0.45) HIF1AHTTTP53MAPTMEN1
SCHEMBL3692887 0.84 MRGPRX4 (0.47) HIF1AMRGPRX4SMN1; SMN2RAB9AHTT
SCHEMBL3696063 0.83 PTGER1 (0.39) HIF1AMRGPRX4SMN1; SMN2HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP claimed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US claimed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US claimed
EP-2231591-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME Kyung Nong Corporation (KR) 2010-09-29 EP claimed
WO-2009072837-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2009-06-11 WO claimed
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed
EP-2231591-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME Kyung Nong Corporation (KR) 2010-09-29 EP disclosed
WO-2009072837-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2009-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 HIF1A 3994/4885MRGPRX4 1060/4885SMN1; SMN2 1736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.