SCHEMBL3688079

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3692887	0.91	MRGPRX4 (0.47)	MRGPRX4TP53HTTSMN1; SMN2RAB9A
	SCHEMBL3688432	0.91	MAPT (0.46)	MRGPRX4TP53HTTSMN1; SMN2RAB9A
	SCHEMBL3694297	0.91	HIF1A (0.42)	MRGPRX4TP53HTTSMN1; SMN2MAPT
	SCHEMBL3683991	0.90	HIF1A (0.54)	MRGPRX4SMN1; SMN2RAB9ANPC1MAPT
	SCHEMBL3686104	0.90	HIF1A (0.41)	MRGPRX4TP53HTTSMN1; SMN2RAB9A
	SCHEMBL16440090	0.89	PTGDR2 (0.42)	MRGPRX4TP53HTTSMN1; SMN2RAB9A
	SCHEMBL3751654	0.86	HIF1A (0.52)	SMN1; SMN2RAB9ANPC1HIF1AMEN1
	SCHEMBL3755609	0.86	NR1H4 (0.45)	TP53HTTMAPTHIF1AMEN1
	SCHEMBL3686125	0.83	TP53 (0.41)	MRGPRX4TP53HTTHIF1AHPGD
	SCHEMBL3697951	0.83	PTGER1 (0.41)	MRGPRX4TP53HTTMAPTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.