SCHEMBL3686130

SCHEMBL3686130

Oc1ccc(C(O)C(Cl)(Cl)Cl)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.45
TSHR P16473 3/20 0.45
ESR2 Q92731 5/20 0.42
CA2 P00918 2/20 0.42
CA1 P00915 1/20 0.42
ESR1 P03372 4/20 0.39
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
HIF1A Q16665 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP19A1 P11511 1/20 0.35
CYP2D6 P10635 1/20 0.35
HPGD P15428 2/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28674464 0.83 AHR (0.42) HSD17B10TSHRSMN1; SMN2CYP2D6LMNA
SCHEMBL7128500 0.83 TDP1 (0.48) HSD17B10TSHRHIF1ACYP1A2ALOX15
SCHEMBL19301757 0.79 HSD17B10 (0.52) HSD17B10TSHRESR2CA2CA1
SCHEMBL29465800 0.76 HSD17B10 (0.54) HSD17B10TSHRESR2CA2CA1
SCHEMBL1596005 0.76 HSD17B10 (0.54) HSD17B10TSHRESR2CA2CA1
SCHEMBL4458922 0.76 HSD17B10 (0.54) HSD17B10TSHRESR2CA2CA1
SCHEMBL30343463 0.76 HSD17B10 (0.54) HSD17B10TSHRESR2CA2CA1
SCHEMBL11789449 0.75 TSHR (0.48) HSD17B10TSHRESR2CA2CA1
SCHEMBL27343824 0.75 CA1 (0.50) HSD17B10TSHRESR2CA2CA1
SCHEMBL7130988 0.74 TRPA1 (0.57) HSD17B10TSHRESR2ESR1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed
EP-2231591-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME Kyung Nong Corporation (KR) 2010-09-29 EP disclosed
WO-2009072837-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2009-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 HSD17B10 1479/4885TSHR 4694/4885ESR2 2967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.