Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 18/20 | 1.00 |
| ▸ | PLA2G6 | O60733 | 1/20 | 1.00 |
| ▸ | PLA2G4C | Q9UP65 | 2/20 | 0.74 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22222834 | 1.00 | PLA2G4A (1.00) | PLA2G4APLA2G6PLA2G4CPTPN1 | |
| SCHEMBL22187659 | 1.00 | PLA2G4A (1.00) | PLA2G4APLA2G6PLA2G4CPTPN1 | |
| SCHEMBL22222879 | 1.00 | PLA2G4A (1.00) | PLA2G4APLA2G6PLA2G4CPTPN1 | |
| SCHEMBL29367824 | 1.00 | PLA2G4A (1.00) | PLA2G4APLA2G6PLA2G4CPTPN1 | |
| SCHEMBL2729842 | 1.00 | PLA2G4A (1.00) | PLA2G4APLA2G6PLA2G4CPTPN1 | |
| SCHEMBL22222880 | 1.00 | PLA2G4A (1.00) | PLA2G4APLA2G6PLA2G4CPTPN1 | |
| SCHEMBL22222825 | 0.78 | PLA2G4A (1.00) | PLA2G4APLA2G6PLA2G4C | |
| SCHEMBL3686144 | 0.77 | PLA2G4A (0.62) | PLA2G4APLA2G6PLA2G4CPTPN1 | |
| SCHEMBL30007459 | 0.73 | PLA2G4A (1.00) | PLA2G4APLA2G6PLA2G4C | |
| SCHEMBL22222831 | 0.70 | PLA2G4A (0.54) | PLA2G4APLA2G6PLA2G4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048893-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20090062530-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-03-05 | — | — | US | disclosed |
| US-7470807-B2 | Suppress production of both prostaglandins and leukotrienes and have reduced side effects; treatment of various inflammatory diseases, autoimmune diseases, allergic diseases, pain and fibrosis; for example, methyl 3-[3-acetylamino-4-cyclopentyloxy-5-(naphthalen-2-yl)phenyl]propionate | ASAHI KASEI PHARMA CORPORATION (JP) | 2008-12-30 | — | — | US | disclosed |
| US-20070213333-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHAMA CORPORATION (JP) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048893-A1 | Substituted arylalkanoic acid derivatives and use thereof | CYSLTR1, CYSLTR2, LTB4R2 | PLA2G4A 460/4885PLA2G6 511/4885PLA2G4C 467/4885 |
| US-20070213333-A1 | Substituted arylalkanoic acid derivatives and use thereof | CYSLTR1, CYSLTR2, LTB4R2 | PLA2G4A 460/4885PLA2G6 511/4885PLA2G4C 467/4885 |
| US-20090062530-A1 | Substituted arylalkanoic acid derivatives and use thereof | CYSLTR1, CYSLTR2, LTB4R2 | PLA2G4A 460/4885PLA2G6 511/4885PLA2G4C 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.