SCHEMBL29367824

SCHEMBL29367824

O=C1NC(=O)/C(=C/c2ccc(C(=O)NC[C@@H]3C[C@@H](SC(c4ccccc4)(c4ccccc4)c4ccccc4)CN3C(=O)c3ccccc3C(=O)c3ccc(F)cc3F)cc2)S1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PLA2G4A P47712 18/20 1.00
PLA2G6 O60733 1/20 1.00
PLA2G4C Q9UP65 2/20 0.74
PTPN1 P18031 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22222834 1.00 PLA2G4A (1.00) PLA2G4APLA2G6PLA2G4CPTPN1
SCHEMBL22187659 1.00 PLA2G4A (1.00) PLA2G4APLA2G6PLA2G4CPTPN1
SCHEMBL22222879 1.00 PLA2G4A (1.00) PLA2G4APLA2G6PLA2G4CPTPN1
SCHEMBL2729842 1.00 PLA2G4A (1.00) PLA2G4APLA2G6PLA2G4CPTPN1
SCHEMBL22222880 1.00 PLA2G4A (1.00) PLA2G4APLA2G6PLA2G4CPTPN1
SCHEMBL3686137 1.00 PLA2G4A (1.00) PLA2G4APLA2G6PLA2G4CPTPN1
SCHEMBL22222825 0.78 PLA2G4A (1.00) PLA2G4APLA2G6PLA2G4C
SCHEMBL3686144 0.77 PLA2G4A (0.62) PLA2G4APLA2G6PLA2G4CPTPN1
SCHEMBL30007459 0.73 PLA2G4A (1.00) PLA2G4APLA2G6PLA2G4C
SCHEMBL22222831 0.70 PLA2G4A (0.54) PLA2G4APLA2G6PLA2G4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4243805-A1 COMBINATION THERAPIES FOR TREATING CORONAVIRUS INFECTION Gbiotech S.À.R.L. (CH) 2023-09-20 EP claimed
WO-2022239725-A1 AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION 日本曹達株式会社 2022-11-17 WO claimed
WO-2022230804-A1 AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION 日本曹達株式会社 2022-11-03 WO claimed
WO-2022029334-A1 COMBINATION THERAPIES FOR TREATING CORONAVIRUS INFECTION GBIOTECH S.À.R.L. (CH) 2022-02-10 WO claimed
US-12590309-B2 Reprogramming of lipid metabolism to inhibit T cell senescence and enhance tumor immunotherapy SAINT LOUIS UNIVERSITY (US) 2026-03-31 US disclosed
EP-3509604-B1 COMBINATION THERAPIES USING IMMUNO-DASH INHIBITORS AND PGE2 ANTAGONISTS TUFTS COLLEGE (US) 2026-02-18 EP disclosed
US-12478609-B2 Combination therapies using immuno-DASH inhibitors and PGE2 antagonists TRUSTEES OF TUFTS COLLEGE (US) 2025-11-25 US disclosed
WO-2025126830-A1 N-SUBSTITUTED OXY-2-AMINOTHIAZOLECARBOXAMIDE COMPOUND OR SALT THEREOF AND AGRICULTURAL AND HORTICULTURAL BACTERICIDE 石原産業株式会社 2025-06-19 WO disclosed
WO-2025121401-A1 PYRAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT 日産化学株式会社 2025-06-12 WO disclosed
WO-2025110227-A1 PYRAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT 日産化学株式会社 2025-05-30 WO disclosed
WO-2025110202-A1 AGENT FOR IMPROVING PLANT NON-BIOLOGICAL STRESS RESISTANCE, METHOD FOR IMPROVING NON-BIOLOGICAL STRESS RESISTANCE, PREPARATION FOR IMPROVING NON-BIOLOGICAL STRESS RESISTANCE, PRODUCT FOR IMPROVING NON-BIOLOGICAL STRESS RESISTANCE, AND PLANT 株式会社クレハ 2025-05-30 WO disclosed
WO-2025110205-A1 AGENT FOR IMPROVING DAMAGE-RECOVERING PROPERTIES OF PLANT, PREPARATION FOR IMPROVING DAMAGE-RECOVERING PROPERTIES, METHOD FOR IMPROVING DAMAGE-RECOVERING PROPERTIES OF PLANT, PLANT BODY, AND AGENT FOR IMPROVING PHYSICAL STRESS RESISTANCE OF PLANT 株式会社クレハ 2025-05-30 WO disclosed
US-20220220482-A1 REPROGRAMMING OF LIPID METABOLISM TO INHIBIT T CELL SENESCENCE AND ENHANCE TUMOR IMMUNOTHERAPY SAINT LOUIS UNIVERSITY (US) 2022-07-14 US disclosed
CN-114467949-A Synergistic composition containing quinolone compounds and application thereof 山东省联合农药工业有限公司 2022-05-13 CN disclosed
WO-2022092084-A1 FUSED HETEROCYCLE DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT クミアイ化学工業株式会社 2022-05-05 WO disclosed
WO-2022065235-A1 IMIDAZO[1,2-A]PYRIDINE COMPOUND AND PEST CONTROL AGENT 日本曹達株式会社 2022-03-31 WO disclosed
US-20220040149-A1 COMBINATION THERAPIES USING IMMUNO-DASH INHIBITORS AND PGE2 ANTAGONISTS TRUSTEES OF TUFTS COLLEGE 2022-02-10 US disclosed
WO-2022029334-A1 COMBINATION THERAPIES FOR TREATING CORONAVIRUS INFECTION GBIOTECH S.À.R.L. (CH) 2022-02-10 WO disclosed
WO-2022032082-A1 BIOINSECTICIDE KANNAR EARTH SCIENCE, LTD. (US) 2022-02-10 WO disclosed
WO-2022024486-A1 HERBICIDE COMPOSITION AND WEED CONTROLLING METHOD 住友化学株式会社 2022-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12478609-B2 Combination therapies using immuno-DASH inhibitors and PGE2 antagonists HPGDS, PTGIS, PTGDR2 PLA2G4A 25/4885PLA2G6 165/4885PLA2G4C 36/4885
US-12590309-B2 Reprogramming of lipid metabolism to inhibit T cell senescence and enhance tumor immunotherapy PLA2G4A, PLA2G2A, PLA2G1B PLA2G4A 1/4885PLA2G6 14/4885PLA2G4C 9/4885
US-20220040149-A1 COMBINATION THERAPIES USING IMMUNO-DASH INHIBITORS AND PGE2 ANTAGONISTS HPGDS, PTGIS, PTGDR2 PLA2G4A 25/4885PLA2G6 165/4885PLA2G4C 36/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.