Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.43 |
| ▸ | HTR1D | P28221 | 9/20 | 0.43 |
| ▸ | HTR1B | P28222 | 9/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692486 | 1.00 | HTR1A (0.43) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL3692417 | 0.90 | CHRNA7 (0.44) | SMN1; SMN2ALDH1A1ABCB1NPC1RAB9A | |
| SCHEMBL3685946 | 0.90 | CHRNA7 (0.44) | SMN1; SMN2ALDH1A1ABCB1NPC1RAB9A | |
| SCHEMBL3686266 | 0.89 | PDE4A (0.43) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL3687529 | 0.88 | SMN1; SMN2 (0.46) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL3693475 | 0.88 | SMN1; SMN2 (0.46) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL3687530 | 0.80 | PTPN1 (0.55) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL3692364 | 0.79 | HTR1A (0.44) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL3687759 | 0.79 | HTR1A (0.44) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL3685949 | 0.79 | CAPN1 (0.47) | SMN1; SMN2ALDH1A1ABCB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |