SCHEMBL368629

SCHEMBL368629

CC(=O)N([SiH3])C(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11377300 0.79
SCHEMBL4888197 0.78
SCHEMBL5136335 0.75
SCHEMBL1925147 0.64 ALDH1A1 (0.50)
SCHEMBL1190178 0.64
SCHEMBL173293 0.64
SCHEMBL4820393 0.64
SCHEMBL1332099 0.64
SCHEMBL30581185 0.64
SCHEMBL9504676 0.64 LMNA (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117377715-A Silicone composition and preparation thereof 美国陶氏有机硅公司 2024-01-09 CN claimed
EP-4363487-A1 SILICONE COMPOSITIONS AND THEIR PREPARATION Dow Silicones Corporation (US) 2024-05-08 EP disclosed
CN-117377715-A Silicone composition and preparation thereof 美国陶氏有机硅公司 2024-01-09 CN disclosed
US-20230365763-A1 ADDITIVE STABILIZATION DOW SILICONES CORPORATION 2023-11-16 US disclosed
US-20230323034-A1 POLYDIORGANOSILOXANE PREPARATION DOW SILICONES CORPORATION 2023-10-12 US disclosed
US-20230272167-A1 SILICONE SEALANT PREPARATION DOW SILICONES CORPORATION 2023-08-31 US disclosed
US-20230272168-A1 POLYDIORGANOSILOXANE PREPARATION DOW SILICONES CORPORATION 2023-08-31 US disclosed
EP-4222191-A1 ADDITIVE STABILIZATION Dow Silicones Corporation (US) 2023-08-09 EP disclosed
EP-4204477-A1 POLYDIORGANOSILOXANE PREPARATION Dow Silicones Corporation (US) 2023-07-05 EP disclosed
EP-4204499-A1 POLYDIORGANOSILOXANE PREPARATION Dow Silicones Corporation (US) 2023-07-05 EP disclosed
US-20100184883-A1 Extenders For Organosiloxane Compositions DOW CORNING LIMITED (GB) 2010-07-22 US disclosed
WO-2009127582-A2 POLYMERIC COMPOSITIONS DOW CORNING CORPORATION (US) 2009-10-22 WO disclosed
EP-2078065-A2 EXTENDERS FOR ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2009-07-15 EP disclosed
CN-100453580-C Organopolysiloxane copolymer and method of preparing same DOW CORNING (US) 2009-01-21 CN disclosed
US-20080312367-A1 Organosiloxane Compositions DOW SILICONES CORPORATION 2008-12-18 US disclosed
WO-2008045417-A2 EXTENDERS FOR ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2008-04-17 WO disclosed
EP-1866374-A1 ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2007-12-19 EP disclosed
WO-2006106360-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 WO disclosed
US-20050272895-A1 Organopolysiloxanes and the use thereof in substances that can be cross-linked at room temperature WACKER-CHEMIE GMBH (DE) 2005-12-08 US disclosed
CN-1665861-A Organopolysiloxane copolymer and method of preparing same DOW CORNING (US) 2005-09-07 CN disclosed