Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056836 | 0.98 | HTT (0.42) | LMNAHTTHIF1ACYP2D6CALM1 | |
| Hydrochloric Acid SCHEMBL11775352 | 0.98 | LMNA (0.42) | LMNAHTTHIF1ACYP2D6CALM1 | |
| SCHEMBL8965651 | 0.98 | HTT (0.42) | LMNAHTTHIF1ACYP2D6CALM1 | |
| Hydrochloric Acid SCHEMBL11771900 | 0.95 | HTT (0.41) | LMNAHTTHIF1ACYP2D6CALM1 | |
| SCHEMBL1017459 | 0.90 | HIF1A (0.46) | HIF1ACYP2D6CALM1TSHRIDO1 | |
| SCHEMBL1964501 | 0.87 | CHRNA7 (0.44) | LMNAHTTHIF1ACYP2D6TP53 | |
| SCHEMBL2063309 | 0.87 | TSHR (0.41) | LMNAHTTHIF1ACYP2D6CALM1 | |
| SCHEMBL14587060 | 0.86 | LMNA (0.46) | LMNAHTTHIF1ACYP2D6POLB | |
| SCHEMBL8965143 | 0.85 | CHRNA7 (0.43) | LMNAHTTHIF1ACYP2D6TP53 | |
| SCHEMBL5944660 | 0.85 | CHRNA7 (0.43) | LMNAHTTHIF1ACYP2D6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674930-B2 | Polyester polyol and polyurethane resin | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2010-03-09 | — | — | US | disclosed |
| US-20090247674-A1 | Polyester polyol and polyurethane resin | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-10-01 | — | — | US | disclosed |
| EP-1921101-A1 | POLYESTER POLYOL AND POLYURETHANE RESIN | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| EP-0758643-B1 | Process for the preparation of ortho-nitro-benzonitriles | CLARIANT GMBH (DE) | 2000-05-17 | — | — | EP | disclosed |
| US-5705674-A | Process for preparing ortho-nitrobenzonitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-06 | — | — | US | disclosed |
| EP-0758643-A2 | Process for the preparation of ortho-nitro-benzonitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-19 | — | — | EP | disclosed |
| EP-0619300-B1 | Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides | BASF AG (DE) | 1996-12-27 | — | — | EP | disclosed |
| US-5510528-A | Preparation of halomethylbenzoly cyanides and novel halomethylbenzoyl cyanides | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
| US-5446199-A | Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl cyanides | BASF AKTIENGESELLSCHAFT (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0619300-A2 | Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides | BASF Aktiengesellschaft (DE) | 1994-10-12 | — | — | EP | disclosed |