SCHEMBL3686336

SCHEMBL3686336

CC(C)c1ccccc1OP(=O)(Oc1ccccc1-c1ccccc1)Oc1ccccc1C(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
USP2 O75604 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 2/20 0.37
ADRB2 P07550 2/20 0.37
S1PR1 P21453 1/20 0.37
ADRA2A P08913 4/20 0.37
ADRA2B P18089 4/20 0.37
ADRA2C P18825 4/20 0.37
PPARA Q07869 2/20 0.36
PKM P14618 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18252 0.87 KMT2A (0.40) LMNAKMT2AALDH1A1ADRA2AADRA2B
SCHEMBL29352226 0.87 KMT2A (0.40) LMNAKMT2AALDH1A1ADRA2AADRA2B
SCHEMBL3688470 0.85 KDM4E (0.41) LMNAUSP2MAPTMAPK1HTT
SCHEMBL473246 0.85 TDP1 (0.44) LMNAUSP2MAPTMAPK1HTT
SCHEMBL6246384 0.83 LMNA (0.40) LMNAMAPTKMT2ACA12CA1
SCHEMBL3690617 0.83 CYP3A4 (0.41) MAPTKMT2APPARAPKMMEN1
SCHEMBL223726 0.82 CYP3A4 (0.41) LMNAMAPK1KMT2AKDM4EMEN1
SCHEMBL222391 0.82 CYP3A4 (0.41) LMNAMAPK1KMT2AKDM4EMEN1
SCHEMBL31105916 0.82 CYP3A4 (0.41) LMNAMAPK1KMT2AKDM4EMEN1
SCHEMBL30524958 0.82 CYP3A4 (0.41) LMNAMAPK1KMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100168299-A1 Flame-Retardant Polyester Fibers and Preparation Process Thereof DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-07-01 US disclosed
EP-1857586-A1 FLAME-RETARDANT POLYESTER FIBER AND METHOD FOR PRODUCING SAME DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-11-21 EP disclosed