Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410795 | 0.87 | LMNA (0.36) | LMNAKMT2ACA12CA1CA2 | |
| SCHEMBL6246385 | 0.86 | INPPL1 (0.46) | LMNAKMT2ACA12CA1CA2 | |
| SCHEMBL29352226 | 0.85 | KMT2A (0.40) | LMNAKMT2AKCNK3KCNK9GABRA1 | |
| SCHEMBL18252 | 0.85 | KMT2A (0.40) | LMNAKMT2AKCNK3KCNK9GABRA1 | |
| SCHEMBL3686336 | 0.83 | LMNA (0.41) | LMNAKMT2ACA12CA1CA2 | |
| SCHEMBL31105916 | 0.77 | CYP3A4 (0.41) | LMNAKMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL222391 | 0.77 | CYP3A4 (0.41) | LMNAKMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL223726 | 0.77 | CYP3A4 (0.41) | LMNAKMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL30524958 | 0.77 | CYP3A4 (0.41) | LMNAKMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL13232511 | 0.77 | APP (0.48) | LMNAKMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344323-A | Reactive flame retardant blends for flexible polyurethane foams | 爱思乐-艾博美国有限公司 | 2020-06-26 | — | — | CN | disclosed |
| EP-1164168-B1 | THERMOPLASTIC RESIN COMPOSITION | DAICEL CHEM (JP) | 2005-07-27 | — | — | EP | disclosed |
| EP-1164168-A1 | THERMOPLASTIC RESIN COMPOSITION | Daicel Chemical Industries, Ltd. (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-4212832-A | REACTING PHOSPHONIC OR PHOSPHORIC ACID ARYL ESTER WITH FORMALDEHYDE AND SULFURIC ACID; FLAME-PROOFING AGENT | BAYER AKTIENGESELLSCHAFT (DE) | 1980-07-15 | — | — | US | disclosed |