Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685725 | 0.94 | KMT2A (0.41) | KMT2AMEN1HPGDNPSR1HTT | |
| SCHEMBL3688122 | 0.91 | KMT2A (0.42) | KMT2AMEN1HPGDNPSR1HTT | |
| SCHEMBL3807653 | 0.90 | KMT2A (0.51) | KMT2AMEN1HPGDNPSR1HTT | |
| SCHEMBL3686786 | 0.89 | KMT2A (0.45) | KMT2AMEN1HPGDNPSR1HTT | |
| SCHEMBL3691099 | 0.88 | KMT2A (0.42) | KMT2AMEN1HPGDNPSR1HTT | |
| SCHEMBL3685959 | 0.86 | KMT2A (0.43) | KMT2AMEN1HPGDNPSR1HTT | |
| SCHEMBL3689656 | 0.85 | KMT2A (0.40) | KMT2AMEN1HPGDNPSR1HTT | |
| SCHEMBL3690192 | 0.85 | KMT2A (0.41) | KMT2AMEN1HPGDNPSR1HTT | |
| SCHEMBL13338203 | 0.85 | KMT2A (0.43) | KMT2AMEN1HPGDNPSR1HTT | |
| SCHEMBL3690999 | 0.84 | KMT2A (0.39) | KMT2AMEN1HPGDNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010044686-A1 | AKR1C3 AS A BIOMARKER, METHODS OF SELECTING AND TREATING PATIENTS BASED UPON AN AKR1C3 PROFILE AND COMPOUNDS FOR USE THEREIN | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-04-22 | — | — | WO | disclosed |