Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692467 | 0.91 | KMT2A (0.43) | KMT2AMEN1HPGDNPSR1HKDC1 | |
| SCHEMBL3691003 | 0.90 | KMT2A (0.42) | KMT2AMEN1HPGDNPSR1HKDC1 | |
| SCHEMBL3686404 | 0.86 | KMT2A (0.42) | KMT2AMEN1HPGDNPSR1HKDC1 | |
| SCHEMBL3691099 | 0.86 | KMT2A (0.42) | KMT2AMEN1HPGDNPSR1HKDC1 | |
| SCHEMBL3685958 | 0.86 | MEN1 (0.36) | KMT2AMEN1HPGDNPSR1HKDC1 | |
| SCHEMBL3685725 | 0.86 | KMT2A (0.41) | KMT2AMEN1HPGDNPSR1HKDC1 | |
| SCHEMBL13338203 | 0.86 | KMT2A (0.43) | KMT2AMEN1HPGDNPSR1HKDC1 | |
| SCHEMBL2970252 | 0.85 | ALDH1A1 (0.43) | KMT2AMEN1HPGDNPSR1HKDC1 | |
| SCHEMBL3806947 | 0.84 | KMT2A (0.36) | KMT2AMEN1HPGDNPSR1HKDC1 | |
| SCHEMBL3688111 | 0.84 | KMT2A (0.45) | KMT2AMEN1HPGDNPSR1HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010044686-A1 | AKR1C3 AS A BIOMARKER, METHODS OF SELECTING AND TREATING PATIENTS BASED UPON AN AKR1C3 PROFILE AND COMPOUNDS FOR USE THEREIN | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-04-22 | — | — | WO | disclosed |