⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469114 | 0.97 | DNM1 (0.46) | — | |
| SCHEMBL9556110 | 0.97 | DNM1 (0.46) | — | |
| SCHEMBL9556001 | 0.97 | DNM1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL9556302 | 0.95 | DNM1 (0.48) | — | |
| SCHEMBL3681305 | 0.92 | — | — | |
| SCHEMBL3621240 | 0.85 | RAB9A (0.43) | — | |
| SCHEMBL2200932 | 0.82 | DNM1 (0.42) | — | |
| SCHEMBL31336402 | 0.82 | RAB9A (0.48) | — | |
| SCHEMBL3622908 | 0.81 | DNM1 (0.68) | — | |
| SCHEMBL3617839 | 0.81 | DNM1 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298504-A1 | AMPHIPHILIC POLYMER AND PROCESSES OF FORMING THE SAME | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-11-25 | — | — | US | disclosed |
| US-4064135-A | Certain thiazole-5-carboxamide compounds | SYNTEX (U.S.A.) INC. (US) | 1977-12-20 | — | — | US | disclosed |
| US-4064257-A | Thiazole cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1977-12-20 | — | — | US | disclosed |