SCHEMBL3687121

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3694297	0.90	HIF1A (0.42)	HIF1AFFAR4FFAR1MRGPRX4RECQL
	SCHEMBL3686965	0.90	HIF1A (0.42)	HIF1AFFAR4MRGPRX4POLBCYP1A2
	SCHEMBL3687896	0.90	HIF1A (0.46)	HIF1AMRGPRX4POLBCYP2C19FOLH1
	SCHEMBL3692887	0.90	MRGPRX4 (0.47)	HIF1AMRGPRX4POLBFOLH1TP53
	SCHEMBL3759934	0.90	HIF1A (0.52)	HIF1AFFAR4FFAR1MRGPRX4RECQL
	SCHEMBL3759933	0.90	HIF1A (0.52)	HIF1AFFAR4FFAR1MRGPRX4RECQL
	SCHEMBL3683351	0.90	HIF1A (0.54)	HIF1APOLBCYP1A2CYP2C9CYP2C19
	SCHEMBL3752980	0.85	NR1H4 (0.45)	HIF1APOLBCYP1A2CYP2C19MEN1
	SCHEMBL3689542	0.85	PTGER1 (0.39)	HIF1AMRGPRX4POLBCYP1A2CYP2C9
	SCHEMBL3759610	0.84	HIF1A (0.51)	HIF1AMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.