SCHEMBL3689542

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3692420	0.90	PPARG (0.42)	MRGPRX4HIF1AFOLH1TP53HTT
	SCHEMBL3697951	0.90	PTGER1 (0.41)	PTGER1PTGER4PTGER3PTGER2MRGPRX4
	SCHEMBL3687121	0.85	HIF1A (0.42)	MRGPRX4HIF1AFOLH1TP53HTT
	SCHEMBL3692329	0.85	PTGER1 (0.37)	PTGER1MRGPRX4HIF1AFOLH1TP53
	SCHEMBL3691179	0.83	TP53 (0.41)	MRGPRX4HIF1AFOLH1TP53HTT
	SCHEMBL3687896	0.83	HIF1A (0.46)	MRGPRX4HIF1AFOLH1HTTPOLB
	SCHEMBL3686965	0.83	HIF1A (0.42)	MRGPRX4HIF1AFOLH1TP53HTT
	SCHEMBL3692887	0.83	MRGPRX4 (0.47)	MRGPRX4HIF1AFOLH1TP53HTT
	SCHEMBL8619689	0.83	PTGDR2 (0.45)	MRGPRX4HIF1ATP53HTTPPARG
	SCHEMBL8619691	0.83	PTGDR2 (0.45)	MRGPRX4HIF1ATP53HTTPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.