SCHEMBL3759610

SCHEMBL3759610

CCON=C(C(=O)O)c1ccccc1COc1cccc(C=C(Br)Br)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.51
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CCNB2 O95067 1/20 0.38
CDK1 P06493 1/20 0.38
CDK4 P11802 1/20 0.38
CCNB1 P14635 1/20 0.38
CCND1 P24385 1/20 0.38
CCNB3 Q8WWL7 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
PKM P14618 1/20 0.38
NR4A2 P43354 1/20 0.38
SPHK2 Q9NRA0 3/20 0.37
SPHK1 Q9NYA1 3/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3754154 0.92 HIF1A (0.49) HIF1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL3751654 0.91 HIF1A (0.52) HIF1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL3752980 0.89 NR1H4 (0.45) HIF1AMEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL3759713 0.88 HIF1A (0.49) HIF1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL3692887 0.84 MRGPRX4 (0.47) HIF1AMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL3687896 0.84 HIF1A (0.46) HIF1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL3687121 0.84 HIF1A (0.42) HIF1AMEN1KMT2ASMN1; SMN2
SCHEMBL3689830 0.84 HIF1A (0.42) HIF1AMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL3686965 0.84 HIF1A (0.42) HIF1AMEN1KMT2AKDM4EALDH1A1
SCHEMBL8618330 0.84 HIF1A (0.50) HIF1AKDM4ESMN1; SMN2NR4A2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP claimed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US claimed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US claimed
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 HIF1A 3994/4885MEN1 33/4885KMT2A 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.