Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690634 | 1.00 | MAPT (0.43) | MAPTMEN1LMNAKMT2ANPSR1 | |
| SCHEMBL3686571 | 0.88 | MAPT (0.47) | MAPTMEN1LMNAKMT2ANPSR1 | |
| SCHEMBL3687806 | 0.88 | MAPT (0.47) | MAPTMEN1LMNAKMT2ANPSR1 | |
| SCHEMBL3694293 | 0.87 | MAOB (0.43) | MAPTMEN1KMT2ATDP1HSP90AA1 | |
| SCHEMBL3697640 | 0.87 | MAOB (0.43) | MAPTMEN1KMT2ATDP1HSP90AA1 | |
| SCHEMBL3688003 | 0.83 | MAOB (0.45) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3683356 | 0.83 | MAOB (0.45) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3687211 | 0.79 | LMNA (0.46) | MAPTMEN1LMNAKMT2ANPSR1 | |
| SCHEMBL3686655 | 0.78 | CXCL12 (0.52) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL3690691 | 0.78 | CXCL12 (0.52) | MAPTMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |