Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687806 | 1.00 | MAPT (0.47) | MAPTL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL3690634 | 0.88 | MAPT (0.43) | MAPTL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL3687209 | 0.88 | MAPT (0.43) | MAPTL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL3691642 | 0.81 | TUBB4A (0.46) | MAPTL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL3692354 | 0.81 | TUBB4A (0.46) | MAPTL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL3686572 | 0.80 | MAPT (0.46) | MAPTL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL3691513 | 0.79 | MAPT (0.73) | MAPTL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL3693538 | 0.79 | MAPT (0.73) | MAPTL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL3691359 | 0.79 | ALDH1A1 (0.58) | MAPTL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL3685710 | 0.79 | ALDH1A1 (0.58) | MAPTL3MBTL1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | claimed |
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |