Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17698523 | 0.86 | GAA (0.30) | — | |
| Hydrochloric Acid SCHEMBL3682026 | 0.84 | LMNA (0.33) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL1685540 | 0.82 | CYP1A2 (0.30) | CYP1A2 | |
| Hydrochloric Acid SCHEMBL3679641 | 0.79 | KMT2A (0.31) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| Ethylene SCHEMBL4976112 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL7272244 | 0.78 | ELANE (0.36) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL17698568 | 0.76 | CYP1A2 (0.30) | CYP1A2 | |
| Hydrochloric Acid SCHEMBL7269966 | 0.74 | ELANE (0.34) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL17698590 | 0.74 | NPC1 (0.31) | ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL6914019 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678866-B2 | Polyethylene composition and process for producing same | TOSOH CORPORATION (JP) | 2010-03-16 | — | — | US | disclosed |
| US-20040214953-A1 | Polyethylene composition and process for producing same | TOSOH CORPORATION | 2004-10-28 | — | — | US | disclosed |