SCHEMBL3687458

SCHEMBL3687458

CCCCN1C(=O)c2cc(Br)c(Br)c(Br)c2C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.36
ATM Q13315 2/20 0.36
MEN1 O00255 2/20 0.36
POLB P06746 2/20 0.36
KMT2A Q03164 2/20 0.36
RGS12 O14924 1/20 0.36
USP2 O75604 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TLR9 Q9NR96 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 5/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 1/20 0.35
PTGS1 P23219 3/20 0.35
PTGS2 P35354 3/20 0.35
MGLL Q99685 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3684269 0.83 CYP1B1 (0.48) MAPTATMMEN1POLBKMT2A
SCHEMBL28962110 0.83 ALDH1A1 (0.43) MAPTATMMEN1POLBKMT2A
SCHEMBL13962726 0.82 PTGS1 (0.41) ALDH1A1PTGS1PTGS2MGLLFAAH
SCHEMBL11003139 0.81 CA1 (0.36) RAB9ACA12CA1CA2CA4
SCHEMBL11000698 0.81 KDM4E (0.47) MAPTMEN1KMT2ARGS12MAPK1
SCHEMBL3683409 0.79 CA12 (0.41) MAPTATMSMN1; SMN2ALDH1A1NPC1
SCHEMBL25221778 0.78 TERT (0.48) MAPTATMMEN1POLBKMT2A
SCHEMBL15908161 0.77 PTGS1 (0.45) ALDH1A1PTGS1PTGS2MGLLFAAH
SCHEMBL16294718 0.77 PTGS1 (0.45) ALDH1A1PTGS1PTGS2MGLLFAAH
SCHEMBL17146892 0.76 CNR1 (0.43) MAPTATMMEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152803-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSITION Sabic Innovative Plastics IP B.V. (NL) 2010-02-17 EP disclosed
US-20080303006-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSTION CITIBANK, N.A., AS COLLATERAL AGENT 2008-12-11 US disclosed
WO-2008149260-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSITION SABIC INNOVATIVE PLASTICS IP B.V. (US) 2008-12-11 WO disclosed
US-5668201-A Flame retardant graft copolymer composition GENERAL ELECTRIC COMPANY (US) 1997-09-16 US disclosed
US-4639486-A POLYETHERIMIDE ESTER AND HALOGENATED MATERIAL GENERAL ELECTRIC COMPANY (US) 1987-01-27 US disclosed