SCHEMBL3687482

SCHEMBL3687482

Cc1cc(-c2cccc(C)c2-c2cc(C)c(N)c(C)c2)cc(C)c1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
CYP3A4 P08684 3/20 0.52
TSHR P16473 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
TP53 P04637 1/20 0.52
CD44 P16070 1/20 0.41
SRC P12931 2/20 0.41
CYP1A1 P04798 1/20 0.40
CYP1A2 P05177 1/20 0.40
FGFR1 P11362 1/20 0.37
RAB9A P51151 2/20 0.36
MYC P01106 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
DPP4 P27487 2/20 0.36
ADORA2A P29274 1/20 0.36
HTR7 P34969 1/20 0.36
NUDT1 P36639 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22450152 0.87 CYP3A4 (0.62) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL3699879 0.87 ALDH1A1 (0.39) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL2026463 0.82 CA1 (0.50) ALDH1A1SRCMYCCA1CA2
SCHEMBL5011792 0.80 HEXA (0.40) ALDH1A1CYP3A4TSHRCD44SRC
SCHEMBL3689049 0.80 DHFR (0.38) ALDH1A1CYP3A4TSHRCD44SRC
SCHEMBL10987129 0.77 ALDH1A1 (0.54) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL30978224 0.75 CA12 (0.49) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL22517355 0.75 CA12 (0.49) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL3355657 0.74 ENPP1 (0.42) TDP1RAB9AMYCCA1CA2
SCHEMBL23854309 0.73 CA1 (0.45) ALDH1A1CYP3A4TSHRTDP1CD44

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741240-B2 Transition metal compounds for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US disclosed
US-20080033125-A1 Transition Metal Compounds for Olefin Polymerization and Oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2008-02-07 US disclosed