SCHEMBL3687895

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3683349	0.92	HIF1A (0.77)	HIF1AMAPTSMN1; SMN2LMNAKMT2A
	SCHEMBL3689950	0.91	HIF1A (0.54)	HIF1APKMMAPTSMN1; SMN2LMNA
	SCHEMBL3689945	0.91	HIF1A (0.54)	HIF1APKMMAPTSMN1; SMN2LMNA
	SCHEMBL3688431	0.91	HIF1A (0.66)	HIF1APKMMAPTSMN1; SMN2LMNA
	SCHEMBL3687120	0.89	HIF1A (0.63)	HIF1AMAPTSMN1; SMN2MEN1KMT2A
	SCHEMBL3686962	0.89	HIF1A (0.63)	HIF1AMAPTSMN1; SMN2KMT2AKDM4E
	SCHEMBL3692884	0.88	HIF1A (0.62)	HIF1AMAPTSMN1; SMN2LMNAKMT2A
	SCHEMBL3687896	0.84	HIF1A (0.46)	HIF1APKMMAPTSMN1; SMN2LMNA
	SCHEMBL3752978	0.83	HIF1A (0.63)	HIF1AMAPTMEN1KMT2AKDM4E
	SCHEMBL3683433	0.83	HIF1A (0.64)	HIF1AMAPTSMN1; SMN2LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.