SCHEMBL3689950

SCHEMBL3689950

CCOc1cc(C=C(Br)Br)ccc1OCc1ccccc1C(=NOC)C(=O)NC

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.54
PKM P14618 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.40
ALDH1A1 P00352 2/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
MAPT P10636 4/20 0.39
HTT P42858 2/20 0.39
POLB P06746 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
CYP2C19 P33261 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3689945 1.00 HIF1A (0.54) HIF1APKMMEN1KMT2ATDP1
SCHEMBL3683433 0.93 HIF1A (0.64) HIF1AKMT2ALMNAALDH1A1SMN1; SMN2
SCHEMBL3683435 0.93 HIF1A (0.64) HIF1AKMT2ALMNAALDH1A1SMN1; SMN2
SCHEMBL3696510 0.91 HIF1A (0.54) HIF1APKMMEN1KMT2ATDP1
SCHEMBL3696515 0.91 HIF1A (0.54) HIF1APKMMEN1KMT2ATDP1
SCHEMBL3687895 0.91 HIF1A (0.66) HIF1APKMMEN1KMT2ATDP1
SCHEMBL3688027 0.89 HIF1A (0.52) HIF1AKMT2AKDM4EALDH1A1SMN1; SMN2
SCHEMBL3688032 0.89 HIF1A (0.52) HIF1AKMT2AKDM4EALDH1A1SMN1; SMN2
SCHEMBL3687974 0.89 HIF1A (0.52) HIF1AMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL3687980 0.89 HIF1A (0.52) HIF1AMEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP claimed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US claimed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US claimed
EP-2231591-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME Kyung Nong Corporation (KR) 2010-09-29 EP claimed
WO-2009072837-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2009-06-11 WO claimed
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
CN-101888993-B Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORP 2013-08-21 CN disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 HIF1A 3994/4885PKM 2395/4885MEN1 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.