SCHEMBL3688103

SCHEMBL3688103

CCO[Si](CC(c1ccccc1)N1CCOCC1)(OCC)OCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 6/20 0.40
KCNA5 P22460 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HSD17B10 Q99714 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MAPT P10636 1/20 0.40
RAB9A P51151 1/20 0.40
HPGD P15428 1/20 0.40
OPRM1 P35372 1/20 0.40
OPRD1 P41143 1/20 0.40
OPRK1 P41145 1/20 0.40
OPRL1 P41146 1/20 0.40
DPP4 P27487 1/20 0.40
CYP3A4 P08684 2/20 0.39
CYP2C19 P33261 1/20 0.39
SLC6A3 Q01959 2/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
CACNA1F O60840 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1711539 0.79 OPRM1 (0.56) TSHRALDH1A1KCNA5OPRM1OPRD1
SCHEMBL11989937 0.76 OPRM1 (0.58) TSHRALDH1A1KCNA5SMN1; SMN2HPGD
SCHEMBL856294 0.72 DPP4 (0.64) TSHRALDH1A1KCNA5DPP4CYP3A4
SCHEMBL20746267 0.72 DPP4 (0.64) TSHRALDH1A1KCNA5DPP4CYP3A4
SCHEMBL1712239 0.72 KCNA5 (0.49) TSHRALDH1A1KCNA5HSD17B10HPGD
SCHEMBL11651599 0.72 OPRL1 (0.58) TSHRALDH1A1KCNA5HSD17B10OPRL1
SCHEMBL16714792 0.72 KMT2A (0.39) TSHRALDH1A1KCNA5SMN1; SMN2MAPT
SCHEMBL23682540 0.72 OPRM1 (0.59) TSHRALDH1A1KCNA5OPRM1OPRD1
SCHEMBL8276876 0.72 ALDH1A1 (0.49) ALDH1A1KCNA5KDM4EHSD17B10SMN1; SMN2
SCHEMBL11989193 0.72 CYP3A4 (0.49) TSHRALDH1A1KCNA5DPP4CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4499747-A1 CROSS-LINKABLE COMPOSITIONS ON THE BASIS OF ORGANOSILICON COMPOUNDS Wacker Chemie AG (DE) 2025-02-05 EP disclosed
WO-2023186261-A1 CROSS-LINKABLE COMPOSITIONS ON THE BASIS OF ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2023-10-05 WO disclosed
EP-2855591-A1 CROSSLINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS Wacker Chemie AG (DE) 2015-04-08 EP disclosed
WO-2013174708-A1 CROSSLINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2013-11-28 WO disclosed
EP-2176351-A1 CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS Wacker Chemie AG (DE) 2010-04-21 EP disclosed
WO-2009019165-A1 CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-02-12 WO disclosed