SCHEMBL3688337

SCHEMBL3688337

FC(F)(Br)C(F)(I)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ALDH1A1 P00352 2/20 0.50
PTPN1 P18031 2/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
KCNN4 O15554 3/20 0.38
KIF11 P52732 1/20 0.37
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.33
BACE1 P56817 1/20 0.32
PGK1 P00558 2/20 0.32
PGK2 P07205 2/20 0.32
PTPN5 P54829 1/20 0.31
TRPV6 Q9H1D0 1/20 0.31
CYP1A2 P05177 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4067866 0.84 ALDH1A1 (0.37) TSHRALDH1A1PTPN1
SCHEMBL11089008 0.77 ALDH1A1 (0.45) TSHRALDH1A1PTPN1KCNN4KIF11
SCHEMBL8579095 0.75 TSHR (0.58) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL3685898 0.74 ALDH1A1 (0.50) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL4117010 0.72 ALDH1A1 (0.55) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL29161115 0.71 KCNN4 (0.45) TSHRALDH1A1PTPN1KCNN4ALOX15
SCHEMBL2549759 0.71 KCNN4 (0.45) TSHRALDH1A1PTPN1KCNN4ALOX15
SCHEMBL127092 0.71 ALDH1A1 (0.61) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL10873447 0.71 ALDH1A1 (0.61) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL1538909 0.67 TSHR (0.65) TSHRALDH1A1PTPN1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100068436-A1 FLUORINE-CONTAINING ELASTOMER FOR MOLDING FUEL SYSTEM PARTS AND COMPOSITION THEREOF Unimatec CO. Ltd (JP) 2010-03-18 US disclosed
EP-2077285-A1 FLUORINATED ELASTOMER FOR MOLDING OF FUEL LINE COMPONENT, AND COMPOSITION COMPRISING THE SAME Unimatec Co., Ltd. (JP) 2009-07-08 EP disclosed
US-20090023863-A1 CROSS-LINKED FLUORINE-CONTAINING COPOLYMER MOLDINGS UNIMATEC CO., LTD. (JP) 2009-01-22 US disclosed
US-6380337-B2 POLYMERIZING MONOMERS DERVIED FROM VINYLIDENE FLUORIDE AND PERFLUORO (METHOXYPROPYL VINYL ETHER), TETRAFLUOROETHYLENE AND PERFLUOROALKYL VINYL ETHER; HEAT, COLD, AND SOLVENT RESISTANT; USED AS OIL SEALS AND FUEL HOSES NIPPON MEKTRON, LTD. (JP) 2002-04-30 US disclosed
US-20020028886-A1 Fluorocopolymer and process for preparing the same NIPPON MEKTRON, LTD. 2002-03-07 US disclosed
US-6281312-B1 USING AN ORGANOHALOGEN COMPOUND NIPPON MEKTRON, LTD. (JP) 2001-08-28 US disclosed
US-20010008922-A1 Fluoroelastomer, production thereof, crosslinkable composition and curing product NIPPON MEKTRON, LTD. (JP) 2001-07-19 US disclosed
US-6160053-A Flourine-containing copolymer composition NIPPON MEDTRON, LIMITED (JP) 2000-12-12 US disclosed
US-6150485-A COPOLYMERIZATION OF VINYLIDENE FLUORIDE, TETRAFLUOROETHYLENE, PERFLUOROALKYL VINYL ETHER AND CHLOROTRIFLUOROETHYLENE POLYMERS IN THE PRESENCE OF IODINE AND BROMINE NIPPON MEKTRON, LIMITED (JP) 2000-11-21 US disclosed
US-6124404-A COPOLYMERIZING TWO MONOMERS FROM THE GROUP CONTAINING A FLUORINATED MONOMERS AND PROPYLENE IN PRESENCE OF SATURATED IODO OR IODOBROMO HYDROCARBON, THEN GRAFT COPOLYMERIZING WITH TETRAFLOROETHYLENE AND POLYFLUOROVINYL ETHER NIPPON MEKTRON LIMITED (JP) 2000-09-26 US disclosed
US-5969066-A TERPOLYMER CONTAINING TETRAFLUOROETHYLENE, PERFLUOROALKYL VINYL ETHER, VINYLIDENE FLUORIDE CROSSLINKED BY A PEROXIDE, LOW TEMPERATURE PROPERTIES, SOLVENT AND CHEMICAL RESISTANCE NIPPON MEKTRON, LIMITED (JP) 1999-10-19 US disclosed
US-5910552-A ELASTOMER COMPRISING TETRAFLUOROETHYLENE, PERFLUOROALKYL PEFLUOROVINYL ETHER, BROMINE-CONTAINING UNSATURATED COMPOUND NIPPON MEKTRON, LIMITED (JP) 1999-06-08 US disclosed
US-5902868-A A FLUOROPOLYMERIC ELASTOMER CONTAINING TETRAFLUOROETHYLENE MONOMER A PERFLUOROVINYL ETHER AND A BROMINE CONTAINING UNSATURATED MONOMER, A POLYFUNCTIONAL UNSATURATED COMPOUND AS COCROSSLINKER AND AN ORGANIC PEROXIDE NIPPON MEKTRON, LIMITED (JP) 1999-05-11 US disclosed
US-5891974-A BLEND CONTAINING AN UNSATURATED BROMINE COMPOUND; HEAT, CHEMICAL RESISTANCE NIPPON MEKTRON, LIMITED (JP) 1999-04-06 US disclosed
EP-0891995-A1 Process for producing fluorine-containing elastomer Nippon Mektron, Limited (JP) 1999-01-20 EP disclosed
EP-0834521-A1 Fluoroelastomer and its cross-linkable composition NIPPON MEKTRON, LTD. (JP) 1998-04-08 EP disclosed
US-5225504-A Perfluoroalkylene-perfluoroalkyl vinyl ether copolymer NOK CORPORATION (JP) 1993-07-06 US disclosed
US-5151492-A Fluorine containing homopolymers or copolymers NIPPON MEKTRON, LIMITED (JP) 1992-09-29 US disclosed
US-4943622-A Bromine and iodine containing hydrocarbon NIPPON MEKTRON, LIMITED (JP) 1990-07-24 US disclosed
US-4748223-A Process for producing peroxide-vulcanizable, fluorine-containing elastomer NIPPON MEKTRON LIMITED (JP) 1988-05-31 US disclosed