Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12361968 | 0.81 | DGAT1 (0.39) | ALDH1A1DGAT1NPSR1CNR2RECQL | |
| SCHEMBL9671887 | 0.78 | ALDH1A1 (0.48) | ALDH1A1NPSR1KDM4ELMNARECQL | |
| SCHEMBL20671829 | 0.77 | DGAT1 (0.37) | ALDH1A1DGAT1NPSR1CNR2 | |
| SCHEMBL1302691 | 0.76 | SMN1; SMN2 (0.44) | ALDH1A1KDM4ELMNARECQLTSHR | |
| SCHEMBL484144 | 0.75 | CNR2 (0.36) | ALDH1A1DGAT1NPSR1CNR2KDM4E | |
| SCHEMBL14902200 | 0.75 | MGAM (0.41) | ALDH1A1DGAT1NPSR1CNR2LMNA | |
| SCHEMBL32683939 | 0.75 | MGAM (0.41) | DGAT1NPSR1CNR2RECQLTSHR | |
| SCHEMBL10042967 | 0.73 | DGAT1 (0.34) | DGAT1NPSR1CNR2RECQL | |
| SCHEMBL8364831 | 0.73 | TSHR (0.40) | ALDH1A1TSHR | |
| SCHEMBL18312018 | 0.72 | DGAT1 (0.39) | ALDH1A1DGAT1NPSR1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176217-A1 | AMINO ACID DERIVATIVES | Proximagen Ltd. (GB) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009007696-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2009-01-15 | — | — | WO | disclosed |