SCHEMBL368875

SCHEMBL368875

Clc1ccc(C(Cl)(c2ccccc2)c2ccccc2)c(Cl)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.41
KCNN4 O15554 4/20 0.39
CYP1A2 P05177 3/20 0.34
CYP2A6 P11509 2/20 0.34
CYP3A4 P08684 3/20 0.33
MAPK1 P28482 3/20 0.33
CYP19A1 P11511 3/20 0.32
KCNA3 P22001 2/20 0.31
KIF11 P52732 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 2/20 0.31
FABP3 P05413 1/20 0.30
TDP1 Q9NUW8 2/20 0.30
HTR2A P28223 2/20 0.30
HTR2C P28335 2/20 0.30
OPRK1 P41145 2/20 0.30
KCNH2 Q12809 2/20 0.30
ADRA1A P35348 1/20 0.30
MEN1 O00255 1/20 0.30
SLC22A1 O15245 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11520709 0.83 TSHR (0.41) TSHRKCNN4CYP1A2CYP2A6CYP3A4
SCHEMBL18485454 0.83 KCNN4 (0.48) TSHRKCNN4CYP1A2CYP2A6CYP3A4
SCHEMBL3239466 0.76 KCNN4 (0.59) TSHRKCNN4CYP1A2CYP2A6CYP3A4
SCHEMBL26214 0.76 KCNN4 (0.59) TSHRKCNN4CYP1A2CYP2A6CYP3A4
SCHEMBL29354141 0.76 KCNN4 (0.59) TSHRKCNN4CYP1A2CYP2A6CYP3A4
Chlorotriphenylmethane SCHEMBL27733223 0.74 KCNN4 (0.57) TSHRKCNN4CYP1A2CYP2A6CYP3A4
Hydrochloric Acid SCHEMBL29532967 0.74 KCNN4 (0.57) TSHRKCNN4CYP1A2CYP2A6CYP3A4
Hydrazine SCHEMBL26109949 0.72 KCNN4 (0.61) TSHRKCNN4CYP1A2CYP2A6CYP3A4
SCHEMBL6415524 0.72 TSHR (0.48) TSHRCYP2A6CYP3A4MAPK1LMNA
SCHEMBL11654993 0.71 KCNN4 (0.59) TSHRKCNN4CYP1A2CYP2A6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4467341-B1 A SYSTEM FOR THE DIRECT ADDITIVE SYNTHESIS FROM UV-INDUCED SOLVATED ELECTRONS IN FEEDSTOCK OF HALOGENATED MATERIAL AND NEGATIVE ELECTRON AFFINITY NANOPARTICLE LOCKHEED CORP (US) 2026-03-18 EP claimed
EP-1713836-B1 PREPARATION METHOD OF POLYMERISATION CATALYST FOR PRODUCTION OF POLYETHYLENE WITH BROAD MOLECULAR WEIGHT DISTRIBUTION HANWHA CHEMICAL CORP (KR) 2014-12-24 EP claimed
EP-1895576-B1 PATTERN FORMING METHOD TOKYO OHKA KOGYO CO LTD (JP) 2014-07-23 EP claimed
EP-1138699-B1 Prepolymerization catalyst for use in gas phase polymerization of olefins and process for producing the same SUMITOMO CHEMICAL CO (JP) 2008-06-18 EP claimed
EP-0614916-B1 Process for producing polyolefin IDEMITSU PETROCHEMICAL CO (JP) 1998-10-07 EP claimed
EP-0332494-A1 Process for the preparation of alkaline-earth titanates RHONE-POULENC CHIMIE (FR) 1989-09-13 EP claimed
CN-118221762-A Preparation method of antibacterial polypeptide derivative 沈旭 2024-06-21 CN disclosed
WO-2012008866-A1 MULTILAYERED NANOCOMPOSITE FOR CAPACITORS AND METHOD FOR MANUFACTURING SAME ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЫО "БAPГAH TEXHOЛOДЖИ" (RU) 2012-01-19 WO disclosed
US-7407686-B2 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION (JP) 2008-08-05 US disclosed
US-20060062936-A1 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION 2006-03-23 US disclosed
US-20030170482-A1 Optical film, polarizing plate and display device utilizing the film, and production method of optical film KONICA CORPORATION (JP) 2003-09-11 US disclosed