Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | CXCL12 | P48061 | 3/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 5/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3689808 | 1.00 | MAOB (0.60) | MAOBMAOACYP1B1CXCL12CXCR4 | |
| SCHEMBL30384875 | 0.89 | BCHE (0.56) | MAOBMAOACYP1B1BCHEACHE | |
| SCHEMBL3691582 | 0.89 | BCHE (0.56) | MAOBMAOACYP1B1BCHEACHE | |
| SCHEMBL25184970 | 0.89 | BCHE (0.56) | MAOBMAOACYP1B1BCHEACHE | |
| SCHEMBL3690207 | 0.89 | BCHE (0.54) | MAOBCYP1B1BCHEACHENPC1 | |
| SCHEMBL3687867 | 0.89 | BCHE (0.54) | MAOBCYP1B1BCHEACHENPC1 | |
| SCHEMBL3688870 | 0.88 | MAOB (0.53) | MAOBMAOACYP1B1CXCL12MAPT | |
| SCHEMBL3695625 | 0.86 | MAOB (0.64) | MAOBCYP1B1CXCL12BCHEACHE | |
| SCHEMBL3689247 | 0.86 | MAOB (0.64) | MAOBCYP1B1CXCL12BCHEACHE | |
| SCHEMBL3686655 | 0.85 | CXCL12 (0.52) | MAOBMAOACYP1B1CXCL12NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | claimed |
| EP-1506158-A2 | DIAMINO-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-02-16 | — | — | EP | claimed |
| WO-2003097576-A2 | DIAMINO-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | claimed |
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |