Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.57 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.57 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 7/20 | 0.55 |
| ▸ | ACHE | P22303 | 5/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.54 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3689247 | 1.00 | MAOB (0.64) | MAOBCYP1B1TNFRSF1AMEN1ALDH1A1 | |
| SCHEMBL3686416 | 0.91 | ABCG2 (0.56) | MAOBCYP1B1BCHEACHECYP3A4 | |
| SCHEMBL3692833 | 0.91 | ABCG2 (0.56) | MAOBCYP1B1BCHEACHECYP3A4 | |
| SCHEMBL3689248 | 0.89 | BCHE (0.60) | MAOBCYP1B1TNFRSF1AMEN1ALDH1A1 | |
| SCHEMBL25184970 | 0.87 | BCHE (0.56) | MAOBCYP1B1MEN1MAPTHSPD1 | |
| SCHEMBL3691582 | 0.87 | BCHE (0.56) | MAOBCYP1B1MEN1MAPTHSPD1 | |
| SCHEMBL30384875 | 0.87 | BCHE (0.56) | MAOBCYP1B1MEN1MAPTHSPD1 | |
| SCHEMBL3690207 | 0.87 | BCHE (0.54) | MAOBCYP1B1TNFRSF1AMAPTKMT2A | |
| SCHEMBL3687867 | 0.87 | BCHE (0.54) | MAOBCYP1B1TNFRSF1AMAPTKMT2A | |
| SCHEMBL3688869 | 0.86 | MAOB (0.60) | MAOBCYP1B1MAPTKMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | claimed |
| EP-1506158-A2 | DIAMINO-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-02-16 | — | — | EP | claimed |
| WO-2003097576-A2 | DIAMINO-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | claimed |
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |
| EP-1506158-A2 | DIAMINO-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097576-A2 | DIAMINO-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |