Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.54 |
| ▸ | ACHE | P22303 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.53 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687867 | 1.00 | BCHE (0.54) | BCHEACHEMAPTMAOBCYP1B1 | |
| SCHEMBL3687869 | 0.92 | BCHE (0.54) | BCHEACHEMAPTMAOBCYP1B1 | |
| SCHEMBL30384875 | 0.90 | BCHE (0.56) | BCHEACHEMAPTMAOBCYP1B1 | |
| SCHEMBL25184970 | 0.90 | BCHE (0.56) | BCHEACHEMAPTMAOBCYP1B1 | |
| SCHEMBL3691582 | 0.90 | BCHE (0.56) | BCHEACHEMAPTMAOBCYP1B1 | |
| SCHEMBL3689808 | 0.89 | MAOB (0.60) | BCHEACHEMAPTMAOBCYP1B1 | |
| SCHEMBL3682843 | 0.89 | P4HB (0.57) | BCHECYP1B1 | |
| SCHEMBL3688869 | 0.89 | MAOB (0.60) | BCHEACHEMAPTMAOBCYP1B1 | |
| SCHEMBL3695625 | 0.87 | MAOB (0.64) | BCHEACHEMAPTMAOBCYP1B1 | |
| SCHEMBL3689247 | 0.87 | MAOB (0.64) | BCHEACHEMAPTMAOBCYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |