Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | EYA2 | O00167 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL1899790 | 0.91 | TDP1 (0.50) | TDP1EYA2APPACEALOX15 | |
| SCHEMBL19206931 | 0.87 | TDP1 (0.31) | TDP1EYA2APPACEALOX15 | |
| SCHEMBL3806335 | 0.86 | TDP1 (0.41) | ABCC4MAPTTDP1EYA2APP | |
| SCHEMBL8768371 | 0.81 | — | — | |
| SCHEMBL19664261 | 0.76 | ABCC4 (0.42) | ABCC4MAPTTDP1ALOX15KDM4E | |
| Nitrilotriacetic Acid SCHEMBL6646334 | 0.74 | TDP1 (0.52) | TDP1EYA2APPACEALOX15 | |
| SCHEMBL28032511 | 0.73 | — | — | |
| Formaldehyde SCHEMBL6118438 | 0.72 | LMNA (0.44) | ABCC4MAPTKDM4ELMNATSHR | |
| SCHEMBL4816014 | 0.72 | LMNA (0.50) | MAPTTDP1KDM4ELMNATSHR | |
| SCHEMBL27023 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313144-A1 | COMBINATIONS COMPRISING ANTI-TM4SF1 ANTIBODIES AND IMMUNOTHERAPEUTIC AGENTS AND METHODS OF USING THE SAME | Angiex, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204565-A1 | COMBINATIONS COMPRISING ANTI-TM4SF1 ANTIBODIES AND IMMUNOTHERAPEUTIC AGENTS AND METHODS OF USING THE SAME | ANGIEX, INC. (US) | 2022-09-29 | — | — | WO | disclosed |
| WO-2010017047-A1 | THERAPEUTIC COMPOUNDS | MERCK & CO., INC. (US) | 2010-02-11 | — | — | WO | disclosed |
| EP-1974949-B1 | Heat-sensitive transfer image-receiving sheet and production method thereof | FUJIFILM CORP (JP) | 2009-11-18 | — | — | EP | disclosed |
| EP-1974949-A1 | Heat-sensitive transfer image-receiving sheet and production method thereof | FUJIFILM Corporation (JP) | 2008-10-01 | — | — | EP | disclosed |