Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.62 |
| ▸ | IDO1 | P14902 | 2/20 | 0.58 |
| ▸ | AGXT | P21549 | 2/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863899 | 0.93 | CHRM2 (0.59) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL4142939 | 0.93 | CHRM2 (0.59) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL5315445 | 0.89 | TAAR1 (0.67) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL21002016 | 0.88 | TAAR1 (0.71) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL21002162 | 0.88 | TAAR1 (0.71) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL29986862 | 0.88 | TAAR1 (0.71) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL21002124 | 0.86 | TAAR1 (0.69) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL723511 | 0.84 | TAAR1 (0.77) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL30080050 | 0.84 | TAAR1 (0.77) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL145383 | 0.83 | CHRM2 (0.65) | CHRM2CHRM1CHRM3TAAR1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710428-A | Benzoxazole kinase inhibitors and methods of use | INTELLIKINE INC | 2015-06-17 | — | — | CN | disclosed |
| CN-102271513-B | Benzoxazole kinase inhibitors and methods of use | INTELLIKINE INC | 2015-02-04 | — | — | CN | disclosed |
| CN-102924458-B | 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors | OSI PHARM INC | 2014-11-05 | — | — | CN | disclosed |
| CN-104080786-A | Treatment regimens using multiple agents | INTELLIKINE LLC | 2014-10-01 | — | — | CN | disclosed |
| CN-103703174-A | Combination pharmaceutical compositions and uses thereof | INTELLIKINE LLC | 2014-04-02 | — | — | CN | disclosed |
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| CN-102985420-A | Cytochrome P450 inhibitors and uses thereof | ANGION BIOMEDICA CORP | 2013-03-20 | — | — | CN | disclosed |
| CN-102924458-A | 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors | OSI PHARM INC | 2013-02-13 | — | — | CN | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |
| CN-1898240-B | Imidazopyrazine tyrosine kinase inhibitors | OSI PHARM INC | 2011-08-03 | — | — | CN | disclosed |
| US-5883125-A | Benzyloxy substituted aromatics and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| CN-1204637-A | Benzyloxy substituted aromatics and their use as fungicides and insecticides | ROHM & HAAS (US) | 1999-01-13 | — | — | CN | disclosed |
| EP-0889024-A1 | Benzyloxy substituted aromatics and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 1999-01-07 | — | — | EP | disclosed |
| EP-0860438-A1 | Fluorine-containing diphenyl acrylamide antimicrobial agents | Shenyang Research Institute of Chemical Industry (CN) | 1998-08-26 | — | — | EP | disclosed |
| EP-0835865-A1 | Dihydropyridazinones and pyridazinones and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |
| CN-1175575-A | Benzyloxy substituted aromatics and their use as fungicides and insecticides | ROHM & HAAS (US) | 1998-03-11 | — | — | CN | disclosed |
| CN-1171392-A | Benzyloxy substitutedaromatics and their use as fungicides and insecticides | ROHM & HAAS (US) | 1998-01-28 | — | — | CN | disclosed |
| EP-0811614-A1 | Benzyloxy substituted aromatics and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0811608-A1 | Benzyloxy substituted aromatics containing an acrylyl moiety and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 1997-12-10 | — | — | EP | disclosed |
| CN-1113232-A | Dithiocarbonimide derivative, fungicidal/insecticidal/acaricidal agent containing said derivative as active ingredient, intermediate for use in producing said derivative from said intermediate | SUMITOMO CHEMICAL CO (JP) | 1995-12-13 | — | — | CN | disclosed |