SCHEMBL3689328

SCHEMBL3689328

C=CC(=O)n1nnc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 9/20 0.58
MGAM O43451 8/20 0.58
AMY1A P0DUB6 8/20 0.58
SI P14410 8/20 0.58
MGAM2 Q2M2H8 8/20 0.58
KMT2A Q03164 3/20 0.58
F2 P00734 2/20 0.58
HPGD P15428 1/20 0.58
SLC9A1 P19634 1/20 0.58
DGAT1 O75907 1/20 0.56
KCNMA1 Q12791 1/20 0.54
MAPT P10636 2/20 0.53
NPSR1 Q6W5P4 2/20 0.53
F12 P00748 5/20 0.53
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HTT P42858 1/20 0.50
MIF P14174 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13518869 0.80 GAA (0.57) GAAMGAMAMY1ASIMGAM2
SCHEMBL2490623 0.80 MAPT (0.61) GAAMGAMAMY1ASIMGAM2
SCHEMBL3462909 0.80 MAPT (0.61) GAAMGAMAMY1ASIMGAM2
SCHEMBL4250719 0.80 GAA (0.68) GAAMGAMAMY1ASIMGAM2
SCHEMBL706083 0.80 MGAM (0.68) GAAMGAMAMY1ASIMGAM2
SCHEMBL2373815 0.79 GAA (0.54) GAAMGAMAMY1ASIMGAM2
SCHEMBL170673 0.78 GAA (0.71) GAAMGAMAMY1ASIMGAM2
SCHEMBL1756653 0.78 DGAT1 (0.69) GAAMGAMAMY1ASIMGAM2
Allyl Alcohol SCHEMBL28517173 0.78 GAA (0.56) GAAMGAMAMY1ASIMGAM2
SCHEMBL461243 0.78 MAPT (0.74) GAAMGAMAMY1ASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100015076-A1 POLYMER STRUCTURE REACTING WITH KERATIN, SYNTHESIS AND USE THEREOF EUDERMIC S.R.L. (IT) 2010-01-21 US claimed
EP-1966282-A1 POLYMER STRUCTURE REACTING WITH KERATIN, SYNTHESIS AND USE THEREOF Eudermic S.r.l (IT) 2008-09-10 EP claimed
WO-2007072521-A1 POLYMER STRUCTURE REACTING WITH KERATIN, SYNTHESIS AND USE THEREOF EUDERMIC S.R.L. (IT) 2007-06-28 WO claimed
US-4228152-A BOUND TO A POLYACRYLIC OR POLYMETHACRYLIC BACKBONE THROUGH ESTER OR AMIDIC BONDS FERRUTI PAOLO 1980-10-14 US claimed
US-4145320-A BOUND TO POLY-ACRYLIC OR METHACRYLIC UNITS THROUGH OXYALKYLENIC, AMINOALKYLENIC, OR OXYAMINOALKYLENIC CHAINS FERRUTI PAOLO 1979-03-20 US claimed
US-4067876-A SUSTAINED RELEASE FERRUTI PAOLO 1978-01-10 US claimed
JP-2088661-A None JP disclosed
JP-3188868-A None JP disclosed
US-20100015076-A1 POLYMER STRUCTURE REACTING WITH KERATIN, SYNTHESIS AND USE THEREOF EUDERMIC S.R.L. (IT) 2010-01-21 US disclosed
US-20100015076-A1 POLYMER STRUCTURE REACTING WITH KERATIN, SYNTHESIS AND USE THEREOF EUDERMIC S.R.L. (IT) 2010-01-21 US disclosed
US-20100015076-A1 POLYMER STRUCTURE REACTING WITH KERATIN, SYNTHESIS AND USE THEREOF EUDERMIC S.R.L. (IT) 2010-01-21 US disclosed
EP-1966282-A1 POLYMER STRUCTURE REACTING WITH KERATIN, SYNTHESIS AND USE THEREOF Eudermic S.r.l (IT) 2008-09-10 EP disclosed
WO-2007142617-A2 FABRICATION AND USE OF BIOCOMPATIBLE MATERIALS FOR TREATING AND REPAIRING HERNIATED SPINAL DISCS SARATECH, INC. (US) 2007-12-13 WO disclosed
US-4223011-A OXYALKYLENE, AMINOALKYLENE; POLYACRYLIC ACID FERRUTI PAOLO 1980-09-16 US disclosed
US-4169923-A HIGH POLYMERS CONTAINING NICOTINIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR USE FERRUTI PAOLO (IT) 1979-10-02 US disclosed
US-4166902-A ESTERIFICATION OF SOLUBLE STARCH WITH NICOTINOYLIMIDAZOLE; SUSTAINED RELEASE BY SLOW HYDROLYSIS IN BIOLOGICAL ENVIRONMENT FERRUTI PAOLO (IT) 1979-09-04 US disclosed
US-4145320-A BOUND TO POLY-ACRYLIC OR METHACRYLIC UNITS THROUGH OXYALKYLENIC, AMINOALKYLENIC, OR OXYAMINOALKYLENIC CHAINS FERRUTI PAOLO 1979-03-20 US disclosed
US-4067876-A SUSTAINED RELEASE FERRUTI PAOLO 1978-01-10 US disclosed
US-3956216-A ACRYLIC ESTER-AZOLIDE-VINYLIDENE POLYMER THE B. F. GOODRICH COMPANY (US) 1976-05-11 US disclosed
US-3955041-A AS BINDERS FOR NONWOVEN FIBERS THE B. F. GOODRICH COMPANY (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100015076-A1 POLYMER STRUCTURE REACTING WITH KERATIN, SYNTHESIS AND USE THEREOF KRT18, PRKDC, CKAP4 GAA 1584/4885MGAM 3445/4885AMY1A 3935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.