Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 8/20 | 0.68 |
| ▸ | AMY1A | P0DUB6 | 8/20 | 0.68 |
| ▸ | GAA | P10253 | 8/20 | 0.68 |
| ▸ | SI | P14410 | 8/20 | 0.68 |
| ▸ | MGAM2 | Q2M2H8 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | F2 | P00734 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.68 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.66 |
| ▸ | FAAH | O00519 | 5/20 | 0.62 |
| ▸ | MGLL | Q99685 | 5/20 | 0.62 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.62 |
| ▸ | F12 | P00748 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250719 | 0.88 | GAA (0.68) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL19357103 | 0.87 | FAAH (0.81) | FAAHMGLL | |
| SCHEMBL170673 | 0.86 | GAA (0.71) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL1756653 | 0.86 | DGAT1 (0.69) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL425580 | 0.84 | FAAH (0.72) | FAAHMGLL | |
| SCHEMBL443789 | 0.84 | MGAM (0.55) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL3840404 | 0.84 | GAA (0.69) | MGAMAMY1AGAASIMGAM2 | |
| Ammonia Solution, Strong SCHEMBL3505685 | 0.84 | GAA (0.69) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL10621117 | 0.84 | GAA (0.64) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL427058 | 0.84 | GAA (0.64) | MGAMAMY1AGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174671-A1 | New 2,3-Dihydro-1H-pyrrolo[3,2-b]pyridine Derivatives as Sigma Ligands | ACONDICIONAMIENTO TARRASENSE (ES) | 2024-05-30 | — | — | US | claimed |
| CN-117480161-A | Novel 2, 3-dihydro-1H-pyrrolo [3,2-b ] pyridine derivatives as sigma ligands | 塔拉森调理公司 | 2024-01-30 | — | — | CN | claimed |
| EP-4305029-A1 | NEW 2,3-DIHYDRO-1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS SIGMA LIGANDS | Acondicionamiento Tarrasense (ES) | 2024-01-17 | — | — | EP | claimed |
| CN-117386893-A | Multilayer composite antibacterial PE water supply pipeline and preparation process thereof | 江苏惠升管业集团有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117229840-A | Water-based memory metal wiredrawing liquid and application thereof | 广州亦盛环保科技有限公司 | 2023-12-15 | — | — | CN | claimed |
| US-20220411374-A1 | ALTERNATE PROCESSES FOR THE PREPARATION OF OMECAMTIV MECARBIL | DR. REDDY'S LABORATORIES LIMITED (IN) | 2022-12-29 | — | — | US | claimed |
| WO-2022189392-A1 | NEW 2,3-DIHYDRO-1H-PYRROLO[3,2-b]PYRIDINE DERIVATIVES AS SIGMA LIGANDS | ACONDICIONAMIENTO TARRASENSE (ES) | 2022-09-15 | — | — | WO | claimed |
| US-11424006-B2 | Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide | PSOMAGEN, INC. (US) | 2022-08-23 | — | — | US | claimed |
| US-20210128498-A1 | TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE | MACROGEN INC. (KR) | 2021-05-06 | — | — | US | claimed |
| WO-2021070124-A1 | ALTERNATE PROCESSES FOR THE PREPARATION OF OMECAMTIV MECARBIL | DR. REDDY’S LABORATORIES LIMITED (IN) | 2021-04-15 | — | — | WO | claimed |
| WO-2016030669-A1 | PROCESS FOR THE PREPARATION OF RIVAROXABAN | CIPLA LIMITED (IN) | 2016-03-03 | — | — | WO | claimed |
| US-9006480-B2 | Process for producing isocyanates | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-04-14 | — | — | US | claimed |
| CN-102844297-B | method for producing isocyanates | 3M INNOVATIVE PROPERTIES CO | 2014-12-10 | — | — | CN | claimed |
| US-20130023694-A1 | PROCESS FOR PRODUCING ISOCYANATES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-01-24 | — | — | US | claimed |
| EP-2377847-A1 | Process for producing isocyanates | 3M Innovative Properties Company (US) | 2011-10-19 | — | — | EP | claimed |
| EP-2014797-A2 | Coating composition for interconnection part of electrode and plasma display panel including the same | Samsung SDI Co., Ltd. (KR) | 2009-01-14 | — | — | EP | claimed |
| EP-1490409-B1 | MODIFIED SACCHARIDES HAVING IMPROVED STABILITY IN WATER | NOVARTIS VACCINES & DIAGNOSTIC (IT) | 2008-12-31 | — | — | EP | claimed |
| US-20080303439-A1 | Coating composition for interconnection part of electrode and plasma display panel including the same | SAMSUNG SDI CO., LTD., A CORP. OF THE REPUBLIC OF KOREA (KR) | 2008-12-11 | — | — | US | claimed |
| EP-0928311-B1 | SHAPING OBJECT WITH REACTIVE FUNCTIONS | BIOTECHNOLOG FORSCHUNG GMBH (DE) | 2003-04-09 | — | — | EP | claimed |
| US-4224439-A | Activated matrix and method of activation | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1980-09-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11424006-B2 | Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide | PNMT, MAOA, HNMT | MGAM 38/4885AMY1A 2168/4885GAA 346/4885 |
| US-20220411374-A1 | ALTERNATE PROCESSES FOR THE PREPARATION OF OMECAMTIV MECARBIL | SI, UMPS, OTC | MGAM 13/4885AMY1A 2048/4885GAA 995/4885 |
| US-20210128498-A1 | TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE | MAOA, PNMT, HNMT | MGAM 28/4885AMY1A 1487/4885GAA 179/4885 |
| US-20240174671-A1 | New 2,3-Dihydro-1H-pyrrolo[3,2-b]pyridine Derivatives as Sigma Ligands | SIGMAR1, OPRD1, TMEM97 | MGAM 4652/4885AMY1A 3139/4885GAA 3874/4885 |
| US-20130023694-A1 | PROCESS FOR PRODUCING ISOCYANATES | IDH2, IDH1, IDH3A | MGAM 116/4885AMY1A 1506/4885GAA 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.