Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619691 | 1.00 | PTGDR2 (0.45) | PTGDR2MRGPRX4TSHRALDH1A1MEN1 | |
| SCHEMBL5360660 | 0.90 | ALDH1A1 (0.46) | PTGDR2MRGPRX4TSHRALDH1A1MEN1 | |
| SCHEMBL8622366 | 0.90 | PTGDR2 (0.44) | PTGDR2MRGPRX4TSHRALDH1A1MEN1 | |
| SCHEMBL8622364 | 0.90 | PTGDR2 (0.44) | PTGDR2MRGPRX4TSHRALDH1A1MEN1 | |
| SCHEMBL54335 | 0.90 | ALDH1A1 (0.46) | PTGDR2MRGPRX4TSHRALDH1A1MEN1 | |
| SCHEMBL8369647 | 0.89 | HIF1A (0.50) | PTGDR2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7543562 | 0.89 | HIF1A (0.50) | PTGDR2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL8369646 | 0.89 | HIF1A (0.50) | PTGDR2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL26650771 | 0.89 | HTT (0.47) | PTGDR2MRGPRX4ALDH1A1MAPTHTT | |
| SCHEMBL349565 | 0.89 | HTT (0.47) | PTGDR2MRGPRX4ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |