Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1954749 | 0.86 | SLC1A3 (0.58) | FOLH1SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL592984 | 0.85 | CA2 (0.55) | FOLH1SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL4899569 | 0.84 | SLC1A3 (0.52) | FOLH1SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL11319029 | 0.84 | SLC1A3 (0.56) | FOLH1SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL12950308 | 0.83 | SLC1A2 (0.60) | SLC1A3SLC1A2SLC1A1TDP1ADRA1A | |
| SCHEMBL5663330 | 0.83 | CA2 (0.53) | FOLH1SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL30586668 | 0.83 | CA2 (0.53) | FOLH1SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL524140 | 0.83 | FOLH1 (0.62) | FOLH1TDP1ADRA1ACHRM1AKR1A1 | |
| SCHEMBL14591440 | 0.83 | FOLH1 (0.62) | FOLH1TDP1ADRA1ACHRM1AKR1A1 | |
| SCHEMBL28224229 | 0.82 | GPR84 (0.51) | SLC1A2SLC1A1CA2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3486263-A2 | SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE | W.R. Grace & CO. - CONN. (US) | 2019-05-22 | — | — | EP | disclosed |
| EP-2185600-B1 | SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE | GRACE W R & CO (US) | 2018-10-31 | — | — | EP | disclosed |
| CN-107915794-A | Catalyst and its application and olefine polymerizing process for the catalytic component of olefinic polymerization and its application and for olefinic polymerization | 中国石油化工股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-104768980-B | The acrylic resin of wide molecular weight distribution | 埃克森美孚化学专利公司 | 2018-04-13 | — | — | CN | disclosed |
| US-9796796-B2 | Self-limiting catalyst composition with No silane | W. R. GRACE & CO.-CONN. (US) | 2017-10-24 | — | — | US | disclosed |
| CN-103476806-B | Catalyst components for the polymerization of olefins | 巴塞尔聚烯烃意大利有限责任公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-102264527-A | Pressure pipes and polyolefin composition for the manufacture thereof | — | 2011-11-30 | — | — | CN | disclosed |
| EP-2185600-A1 | SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE | Dow Global Technologies Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009029447-A1 | SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-03-05 | — | — | WO | disclosed |
| CN-100443536-C | Polyolefin articles | BASELL POLIOLEFINE SRL (IT) | 2008-12-17 | — | — | CN | disclosed |
| CN-1833000-A | Polyolefin articles | BASELL POLIOLEFINE SRL (IT) | 2006-09-13 | — | — | CN | disclosed |