Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776625 | 0.95 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4902729 | 0.95 | THRB (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10982125 | 0.90 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8678908 | 0.90 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29516143 | 0.90 | THRB (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL30512919 | 0.87 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1532811 | 0.87 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL6547122 | 0.86 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2505517 | 0.84 | THRB (0.52) | TSHRTHRBPOLBAPEX1HTT | |
| 1,6-Hexanediol SCHEMBL29137905 | 0.84 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070879-A1 | REDUCTION OF ANTIBIOTIC ACTIVITY OR CONCENTRATION IN BIOLOGICAL SAMPLES USING MOLECULARLY IMPRINTED POLYMERS | BECTON, DICKINSON AND COMPANY (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120012530-A1 | MOLECULARLY IMPRINTED POLYMER ION EXCHANGE RESINS | JOHNS HOPKINS UNIVERSITY (US) | 2012-01-19 | — | — | US | disclosed |
| EP-1733211-B1 | PROCESSABLE MOLECULARLY IMPRINTED POLYMERS | UNIV JOHNS HOPKINS (US) | 2012-01-11 | — | — | EP | disclosed |
| US-8058208-B2 | Beads having properly sized cavities for selective sequestering of specific inorganic ions from liquid medium; suspension copolymerization of styrene, divinylbenzene and reactive complex then removing metal ion; water clean up | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-11-15 | — | — | US | disclosed |
| EP-1800186-B1 | AN IMPRINTED POLYMER SUPPORT | AGENCY SCIENCE TECH & RES (SG) | 2011-05-11 | — | — | EP | disclosed |
| WO-2011014923-A1 | MOLECULARLY IMPRINTED POLYMERS, METHODS FOR THEIR PRODUCTION AND USES THEREOF | MONASH UNIVERSITY (AU) | 2011-02-10 | — | — | WO | disclosed |
| US-20080144002-A1 | Molecularly Imprinted Polymer Sensor Device | JOHNS HOPKINS UNIVERSITY | 2008-06-19 | — | — | US | disclosed |
| US-4424331-A | Stable, anaerobically-hardening adhesives containing mixed amine oxide/HN-acidic compound initiators | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1984-01-03 | — | — | US | disclosed |