SCHEMBL1532811

SCHEMBL1532811

C=C(C)C(=O)OCCO.C=C(CCC)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.47
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.34
ACHE P22303 1/20 0.34
MGLL Q99685 1/20 0.32
FFAR3 O14843 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10982125 0.90 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL29516143 0.90 THRB (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5851844 0.90 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL368972 0.87 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5505311 0.86 THRB (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9776625 0.85 TSHR (0.45) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8678908 0.84 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
Propanol SCHEMBL28040663 0.84 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
Butane SCHEMBL9100855 0.84 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL9453862 0.84 THRB (0.53) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9248216-B2 Medical devices for delivery of therapeutic agents BOSTON SCIENTIFIC SCIMED, INC. (US) 2016-02-02 US disclosed
US-20130164348-A1 MEDICAL DEVICES FOR DELIVERY OF THERAPEUTIC AGENTS BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-06-27 US disclosed
US-8361143-B2 Medical devices for delivery of therapeutic agents BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-01-29 US disclosed
US-8211455-B2 Implantable or insertable medical devices for controlled delivery of a therapeutic agent BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-07-03 US disclosed
US-20110123594-A1 Implantable or Insertable Medical Devices For Controlled Delivery of a Therapeutic Agent BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-05-26 US disclosed
US-7939094-B2 Comprises implantable/insertable implants (catheter, stents) BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-05-10 US disclosed
US-7923509-B2 Drug delivery compositions and medical devices containing block copolymer BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-04-12 US disclosed
US-7901702-B2 Implantable or insertable medical devices for controlled delivery of a therapeutic agent BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-08 US disclosed
US-20100092540-A1 DRUG DELIVERY COMPOSITIONS AND MEDICAL DEVICES CONTAINING BLOCK COPOLYMER BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-04-15 US disclosed
US-7622530-B2 Drug delivery compositions and medical devices containing block copolymer BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-11-24 US disclosed
US-20030228346-A1 Sustained release of superoxide dismutase mimics from implantable or insertable medical devices BOSTON SCIENTIFIC SCIMED, INC. 2003-12-11 US disclosed
WO-2003090806-A1 MODULATION OF THERAPEUTIC AGENT RELEASE FROM A POLYMERIC CARRIER USING SOLVENT-BASED TECHNIQUES SCIMED LIFE SYSTEMS, INC. (US) 2003-11-06 WO disclosed
US-20030203000-A1 Modulation of therapeutic agent release from a polymeric carrier using solvent-based techniques BOSTON SCIENTIFIC SCIMED, INC. 2003-10-30 US disclosed
US-20030171496-A1 Drug delivery compositions and medical devices containing block copolymer PINCHUK LEONARD (US) 2003-09-11 US disclosed
EP-1341565-A2 DRUG DELIVERY COMPOSITIONS AND COATED MEDICAL DEVICES Boston Scientific Limited (BB) 2003-09-10 EP disclosed
WO-2003061718-A2 MEDICAL ARTICLES HAVING ENZYMATIC SURFACES FOR LOCALIZED THERAPY SCIMED LIFE SYSTEMS, INC. (US) 2003-07-31 WO disclosed
US-20030138415-A1 Medical articles having enzymatic surfaces for localized therapy BOSTON SCIENTIFIC SCIMED, INC. 2003-07-24 US disclosed
US-6545097-B2 Biocompatible block copolymer comprising one or more elastomeric blocks and one or more thermoplastic blocks connected by a seed polymer SCIMED LIFE SYSTEMS, INC. 2003-04-08 US disclosed
US-20020107330-A1 Drug delivery compositions and medical devices containing block copolymer BOSTON SCIENTIFIC SCIMED, INC. 2002-08-08 US disclosed
WO-2002047731-A2 DRUG DELIVERY COMPOSITIONS AND COATED MEDICAL DEVICES SCIMED LIFE SYSTEMS, INC. (US) 2002-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100092540-A1 DRUG DELIVERY COMPOSITIONS AND MEDICAL DEVICES CONTAINING BLOCK COPOLYMER VEGFA, VMA21, ABCB1 TSHR 3134/4885THRB 487/4885POLB 320/4885
US-20030203000-A1 Modulation of therapeutic agent release from a polymeric carrier using solvent-based techniques ABCB11, LPXN, LIPA TSHR 1872/4885THRB 2666/4885POLB 1308/4885
US-20030228346-A1 Sustained release of superoxide dismutase mimics from implantable or insertable medical devices SOD1, SOD3, CAT TSHR 3220/4885THRB 3358/4885POLB 1790/4885
US-20030138415-A1 Medical articles having enzymatic surfaces for localized therapy CYP21A2, CYP17A1, MGAM TSHR 2347/4885THRB 2797/4885POLB 3376/4885
US-20110123594-A1 Implantable or Insertable Medical Devices For Controlled Delivery of a Therapeutic Agent MIF, PAICS, IDUA TSHR 2108/4885THRB 1955/4885POLB 4396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.