SCHEMBL3689752

SCHEMBL3689752

Clc1c(Cl)c(Cl)c(Oc2ccccc2)c(Cl)c1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.55
TSHR P16473 1/20 0.55
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GLA P06280 1/20 0.46
RHEB Q15382 2/20 0.44
NR1H2 P55055 2/20 0.42
BAX Q07812 1/20 0.42
MAOA P21397 1/20 0.42
NSD2 O96028 1/20 0.42
HSP90AA1 P07900 1/20 0.42
HKDC1 Q2TB90 1/20 0.42
TLR9 Q9NR96 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
DPP4 P27487 1/20 0.39
MEN1 O00255 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10975434 0.87 MAOA (0.43) LTA4HTSHRKMT2AMAPTKDM4E
SCHEMBL10944616 0.86 LTA4H (0.46) LTA4HTSHRKMT2AMAPTKDM4E
SCHEMBL10946442 0.86 MAOA (0.46) LTA4HTSHRKMT2AMAPTKDM4E
SCHEMBL28697139 0.84 LTA4H (0.44) LTA4HTSHRKMT2AMAPTKDM4E
SCHEMBL14157197 0.84 LTA4H (0.45) LTA4HTSHRKMT2AMAPTKDM4E
SCHEMBL10948313 0.84 MAOA (0.45) LTA4HTSHRKMT2AMAPTKDM4E
SCHEMBL6921888 0.81 KMT2A (0.50) LTA4HTSHRKMT2AMAPTKDM4E
SCHEMBL17273646 0.80 LTA4H (0.73) LTA4HTSHRKMT2AMAPTKDM4E
SCHEMBL10983781 0.80 KMT2A (0.47) LTA4HTSHRKMT2AMAPTKDM4E
SCHEMBL8694197 0.80 KMT2A (0.41) LTA4HTSHRKMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5357027-A Fireproof, heat resistant, impact resistant molding materials IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-10-18 US claimed
US-4490266-A Process for the preparation of liquids of low inflammability and high viscosity index and the use thereof BAYER AKTIENGESELLSCHAFT (DE) 1984-12-25 US claimed
EP-2152803-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSITION Sabic Innovative Plastics IP B.V. (NL) 2010-02-17 EP disclosed
US-20080303006-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSTION CITIBANK, N.A., AS COLLATERAL AGENT 2008-12-11 US disclosed
WO-2008149260-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSITION SABIC INNOVATIVE PLASTICS IP B.V. (US) 2008-12-11 WO disclosed
EP-0563342-B1 ELECTRORHEOLOGICAL FLUIDS CONTAINING ELECTRONICALLY CONDUCTIVE POLYMERS LUBRIZOL CORP (US) 1997-11-26 EP disclosed
US-5668201-A Flame retardant graft copolymer composition GENERAL ELECTRIC COMPANY (US) 1997-09-16 US disclosed
EP-0562067-B1 ELECTRORHEOLOGICAL FLUIDS CONTAINING POLYANILINES LUBRIZOL CORP (US) 1997-04-09 EP disclosed
US-5595680-A Electrorheological fluids containing polyanilines THE LUBRIZOL CORPORATION (US) 1997-01-21 US disclosed
US-5451632-A Polycarbonate-polyorganosiloxane copolymer and a resin composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-09-19 US disclosed
US-5437806-A Nonaqueous fluids comprising a hydrophobic liquid phase and a dispersed particle phase of polyaniline; flotational coupling devices, e.g. auto clutches, motors, transmissions THE LUBRIZOL CORPORATION (US) 1995-08-01 US disclosed
US-4639486-A POLYETHERIMIDE ESTER AND HALOGENATED MATERIAL GENERAL ELECTRIC COMPANY (US) 1987-01-27 US disclosed
EP-0184444-A2 Permanently antistatic thermoplastic molding composition CELANESE CORPORATION (US) 1986-06-11 EP disclosed
US-4579902-A POLYBUTYLENE TEREPHTHALATE RESIN, DOPANT, CARBON FIBERS CELANESE CORPORATION (US) 1986-04-01 US disclosed
US-4490266-A Process for the preparation of liquids of low inflammability and high viscosity index and the use thereof BAYER AKTIENGESELLSCHAFT (DE) 1984-12-25 US disclosed
EP-0096281-A2 Process for the preparation of hardly inflammable liquids with a high viscosity index, and their application BAYER AG (DE) 1983-12-21 EP disclosed
US-4359394-A HALOGENATED AROMATICS FOR COMPRESSORS THERMO KING CORPORATION (US) 1982-11-16 US disclosed
US-4254242-A POLYESTER, POLYAMIDE, AROMATIC HALOGEN COMPOUND UNITIKA LTD. (JP) 1981-03-03 US disclosed
US-4171330-A A BISPHENOL ISOPHTHALATE-TEREPHTHALATE COPOLYESTER BLENDED WITH A LINEAR POLYAMIDE OR POLYLACTAM, A POLYALKYLENE PHENYLENE ESTER OR ESTER ETHER AND AN AROMATIC HALOGEN COMPOUND UNITIKA LTD. (JP) 1979-10-16 US disclosed
US-4010219-A HALOGENATED DIPHENYL ETHER TORAY INDUSTRIES, INC. (JA) 1977-03-01 US disclosed