Stearic Acid

Stearic Acid

SCHEMBL3689753

CC1CCC(NC(=O)CC(CC(=O)NC2CCC(C)CC2)C(=O)NC2CCC(C)CC2)CC1.CCCCCCCCCCCCCCCCCC(=O)[O-].CCCCCCCCCCCCCCCCCC(=O)[O-].[Mg+2]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
CNR2 P34972 4/20 0.39
CNR1 P21554 3/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
FABP3 P05413 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Stearic Acid SCHEMBL3694415 0.98 GNAI3 (0.43) GNAI3GNAO1GNAI1CNR2CNR1
Stearic Acid SCHEMBL3686452 0.98 GNAI3 (0.43) GNAI3GNAO1GNAI1CNR2CNR1
Stearic Acid SCHEMBL3690322 0.98 GNAI3 (0.43) GNAI3GNAO1GNAI1CNR2CNR1
Stearic Acid SCHEMBL3696590 0.98 GNAI3 (0.46) GNAI3GNAO1GNAI1CNR2CNR1
SCHEMBL3694347 0.94 NFKB1 (0.46) GNAI3GNAO1GNAI1CNR2CNR1
Zinc Ion SCHEMBL3692705 0.91 NFKB1 (0.46) GNAI3GNAO1GNAI1CNR2CNR1
SCHEMBL3689865 0.91 NFKB1 (0.46) GNAI3GNAO1GNAI1CNR2CNR1
Potassium Ion SCHEMBL3686752 0.91 NFKB1 (0.46) GNAI3GNAO1GNAI1CNR2CNR1
SCHEMBL3694269 0.91 NFKB1 (0.49) GNAI3GNAO1GNAI1CNR2CNR1
Stearic Acid SCHEMBL3695324 0.86 CA12 (0.38) GNAI3GNAO1GNAI1CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723413-B2 Method and composition for control of crystallization rate of polyolefin resin, resin composition and resin molding NEW JAPAN CHEMICAL CO., LTD. (JP) 2010-05-25 US disclosed
US-20070142514-A1 Method and composition for control of crystallization rate of polyolefin resin, resin composition and resin molding NEW JAPAN CHEMICAL CO., LTD. (JP) 2007-06-21 US disclosed