SCHEMBL3689830

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3687655	0.91	HIF1A (0.43)	HIF1AMAPTSMN1; SMN2NR4A2NPC1
	SCHEMBL3752980	0.85	NR1H4 (0.45)	HIF1AMAPTSMN1; SMN2NR4A2NPC1
	SCHEMBL3759610	0.84	HIF1A (0.51)	HIF1ASMN1; SMN2NR4A2NPC1RAB9A
	SCHEMBL3692329	0.83	PTGER1 (0.37)	HIF1AOPRL1TP53HTTMRGPRX4
	SCHEMBL3689826	0.83	HIF1A (0.65)	HIF1AMAPTSMN1; SMN2OPRL1MAOA
	SCHEMBL5076407	0.82	HIF1A (0.39)	HIF1AMAPTSMN1; SMN2NR4A2NPC1
	SCHEMBL3691179	0.82	TP53 (0.41)	HIF1AMAPTTP53HTTMRGPRX4
	SCHEMBL3751696	0.81	NR1H4 (0.43)	HIF1AMAPTNR4A2TP53HTT
	SCHEMBL3696550	0.81	HIF1A (0.52)	HIF1AMAPTSMN1; SMN2OPRL1MAOA
	SCHEMBL3696553	0.81	HIF1A (0.52)	HIF1AMAPTSMN1; SMN2OPRL1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.