SCHEMBL3689826

SCHEMBL3689826

CO/N=C(/C(=O)OC)c1ccccc1COc1ccc(C=C(Br)Br)c(Cl)c1

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.65
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
OPRL1 P41146 4/20 0.35
MAPT P10636 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3687653 0.91 HIF1A (0.66) HIF1AMAOAMAOBOPRL1MAPT
SCHEMBL3696550 0.91 HIF1A (0.52) HIF1AMAOAMAOBOPRL1MAPT
SCHEMBL3696553 0.91 HIF1A (0.52) HIF1AMAOAMAOBOPRL1MAPT
SCHEMBL3752978 0.84 HIF1A (0.63) HIF1AMAPT
SCHEMBL3759608 0.83 HIF1A (0.76) HIF1A
SCHEMBL3689830 0.83 HIF1A (0.42) HIF1AMAOAMAOBOPRL1MAPT
SCHEMBL3686580 0.82 HIF1A (0.53) HIF1AMAOAMAOBOPRL1MAPT
SCHEMBL5076404 0.82 HIF1A (0.58) HIF1AMAOAMAOBMAPTSMN1; SMN2
SCHEMBL3686581 0.82 HIF1A (0.53) HIF1AMAOAMAOBOPRL1MAPT
SCHEMBL3692328 0.82 HIF1A (0.55) HIF1AOPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP claimed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US claimed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US claimed
EP-2231591-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME Kyung Nong Corporation (KR) 2010-09-29 EP claimed
WO-2009072837-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2009-06-11 WO claimed
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-25 US disclosed
EP-2231591-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME Kyung Nong Corporation (KR) 2010-09-29 EP disclosed
WO-2009072837-A2 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2009-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298593-A1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME CYP51A1, MSMO1, MTMR1 HIF1A 3994/4885MAOA 207/4885MAOB 806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.