Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.38 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.36 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408483 | 0.90 | PLA2G2C (0.41) | PLA2G2CITPR3ITPR1ALDH1A1GABBR2 | |
| SCHEMBL532831 | 0.87 | PPARD (0.39) | PLA2G2CPPARDTSHRBTN3A1 | |
| SCHEMBL18015062 | 0.86 | ITPR3 (0.41) | PLA2G2CITPR3ITPR1ALDH1A1GABBR2 | |
| SCHEMBL6393988 | 0.86 | PLA2G2C (0.33) | PLA2G2CITPR3ITPR1PPARDTSHR | |
| SCHEMBL8768479 | 0.86 | PLA2G2C (0.38) | PLA2G2CITPR3ITPR1ALDH1A1GABBR2 | |
| Hydrochloric Acid SCHEMBL31256693 | 0.85 | PPARD (0.37) | PLA2G2CPPARDTSHRBTN3A1 | |
| SCHEMBL27635097 | 0.85 | PPARD (0.37) | PLA2G2CPPARDTSHRBTN3A1 | |
| Ammonia Solution, Strong SCHEMBL1880136 | 0.85 | PPARD (0.37) | PLA2G2CPPARDTSHRBTN3A1 | |
| Ethylene Glycol SCHEMBL28134638 | 0.85 | PPARD (0.37) | PLA2G2CPPARDTSHRBTN3A1 | |
| SCHEMBL17930259 | 0.85 | PPARD (0.37) | PLA2G2CPPARDTSHRBTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332776-B | Cationic lipid compound, and composition and application thereof | 上海艺妙达生物科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-116332776-A | Cationic lipid compound, and composition and application thereof | 上海艺妙达生物科技有限公司 | 2023-06-27 | — | — | CN | claimed |
| US-8628961-B2 | Small molecule antagonists of phosphatidylinositol-3,4,5-triphosphate (PIP3) and uses thereof | TUFTS UNIVERSITY (US) | 2014-01-14 | — | — | US | claimed |
| US-20120136033-A1 | Small Molecule Antagonists of Phosphatidylinositol-3,4,5-Triphosphate (PIP3) and Uses Thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-05-31 | — | — | US | claimed |
| US-20120016033-A1 | Small Molecule Antagonists of Phosphatidylinositol-3,4,5-Triphosphate (PIP3) and Uses Thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-01-19 | — | — | US | claimed |
| WO-2011022028-A2 | SMALL MOLECULE ANTAGONISTS OF PHOSPHATIDYLINOSITOL-3, 4, 5-TRIPHOSPHATE (PIP3) AND USES THEREOF | TUFTS UNIVERSITY (US) | 2011-02-24 | — | — | WO | claimed |
| CN-114404615-B | Polypeptide nano micelle preparation, and preparation method and application thereof | 国家纳米科学中心 | 2024-05-24 | — | — | CN | disclosed |
| CN-116332776-B | Cationic lipid compound, and composition and application thereof | 上海艺妙达生物科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-116650621-A | Targeting polypeptide nano-composite, preparation method and application thereof | 国家纳米科学中心 | 2023-08-29 | — | — | CN | disclosed |
| CN-116332776-A | Cationic lipid compound, and composition and application thereof | 上海艺妙达生物科技有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-9040585-B2 | Small molecule antagonists of phosphatidylinositol-3,4,5-triphosphate (PIP3) and uses thereof | TUFTS UNIVERSITY (US) | 2015-05-26 | — | — | US | disclosed |
| WO-2014187878-A1 | INTERNAL DNA STANDARDS FOR ASSAYS USING MICRO-ELECTROPHORESIS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-11-27 | — | — | WO | disclosed |
| US-20140187639-A1 | Small Molecule Antagonists of Phosphatidylinositol-3,4,5-Triphosphate (PIP3) and Uses Thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-07-03 | — | — | US | disclosed |
| US-7790286-B2 | External modification of composite organic inorganic nanoclusters | INTEL CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090069481-A1 | EXTERNAL MODIFICATION OF COMPOSITE ORGANIC INORGANIC NANOCLUSTERS | ZHANG JINGWU | 2009-03-12 | — | — | US | disclosed |
| US-20080152534-A1 | Self-assembling raman-active nanoclusters | INTEL CORPORATION | 2008-06-26 | — | — | US | disclosed |
| US-7361410-B2 | External modification of composite organic inorganic nanoclusters comprising raman active organic compound | INTEL CORPORATION (US) | 2008-04-22 | — | — | US | disclosed |
| US-20080076119-A9 | Composite organic inorganic nanoclusters | SUN LEI | 2008-03-27 | — | — | US | disclosed |
| US-20060234248-A1 | Composite organic inorganic nanoclusters | INTEL CORPORATION | 2006-10-19 | — | — | US | disclosed |
| US-20060073336-A1 | External modification of composite organic inorganic nanoclusters | INTEL CORPORATION | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016033-A1 | Small Molecule Antagonists of Phosphatidylinositol-3,4,5-Triphosphate (PIP3) and Uses Thereof | PIP5K1A, PIP5K1B, PIP4K2A | PLA2G2C 113/4885ITPR3 48/4885ITPR1 81/4885 |
| US-20120136033-A1 | Small Molecule Antagonists of Phosphatidylinositol-3,4,5-Triphosphate (PIP3) and Uses Thereof | PIP5K1A, PIP5K1B, PIP5K1C | PLA2G2C 176/4885ITPR3 58/4885ITPR1 87/4885 |
| US-20140187639-A1 | Small Molecule Antagonists of Phosphatidylinositol-3,4,5-Triphosphate (PIP3) and Uses Thereof | PIP5K1A, PIP5K1B, PIP4K2A | PLA2G2C 113/4885ITPR3 48/4885ITPR1 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.